1 Preface
2 Research Methodology and Market Definitions
3 Executive Summary
4 Global Biopharmaceutical Market: Key Trends
4.1 Biopharmaceuticals are Growing Faster than Small Molecule Drugs
4.2 Growth of Biosimilars will Push Volumes and Introduce New Players in this Market
4.3 A Rich Biopharmaceutical Pipeline will Drive the Capacity Demand in the Coming Years
4.4 Increasing Trends in Mergers and Acquisitions will Increase Redundant Capacities
4.5 Increasing Focus on Personalized Medicines and High Value Low Volume Markets
4.6 Higher Titers will Reduce Capacity Demand
4.7 Growth in the Use of Cost Effective Disposable Technologies
4.8 Despite Sufficient Global Capacity, Its Uneven Distribution will Continue to Spur Demand
5 Global Biopharmaceutical Market: Industry Performance
5.1 Current and Historical Sales Trends
5.2 Market Breakup by Region
5.3 Market Breakup by Expression Systems
5.4 Market Breakup by Product Type
5.5 Market Outlook
5.6 SWOT Analysis
5.6.1 Strengths
5.6.2 Weaknesses
5.6.3 Opportunities
5.6.4 Threats
5.7 Value Chain Analysis
5.8 Porter’s Five Forces Analysis
5.8.1 Overview
5.8.2 Bargaining Power of Buyers
5.8.3 Bargaining Power of Suppliers
5.8.4 Degree of Competition
5.8.5 Threat of New Entrants
5.8.6 Threat of Substitutes
6 Regional Biopharmaceutical Market Analysis
6.1 United States
6.1.1 Current and Historical Sales Trends
6.1.2 Market Outlook
6.2 Canada
6.2.1 Current and Historical Sales Trends
6.2.2 Market Outlook
6.3 United Kingdom
6.3.1 Current and Historical Sales Trends
6.3.2 Market Outlook
6.4 Germany
6.4.1 Current and Historical Sales Trends
6.4.2 Market Outlook
6.5 France
6.5.1 Current and Historical Sales Trends
6.5.2 Market Outlook
6.6 Italy
6.6.1 Current and Historical Sales Trends
6.6.2 Market Outlook
6.7 Spain
6.7.1 Current and Historical Sales Trends
6.7.2 Market Outlook
6.8 Russia
6.8.1 Current and Historical Sales Trends
6.8.2 Market Outlook
6.9 Brazil
6.9.1 Current and Historical Sales Trends
6.9.2 Market Outlook
6.10 Australia
6.10.1 Current and Historical Sales Trends
6.10.2 Market Outlook
7 Global Biopharmaceutical Manufacturing Industry
7.1 Current and Historical Manufacturing Capacity Trends
7.2 Impact of COVID-19
7.3 Market Breakup by Region
7.3.1 North America
7.3.1.1 Current and Historical Manufacturing Capacity Trends
7.3.1.2 Market Outlook
7.3.2 Europe
7.3.2.1 Current and Historical Manufacturing Capacity Trends
7.3.2.2 Market Outlook
7.3.3 Asia
7.3.3.1 Current and Historical Manufacturing Capacity Trends
7.3.3.2 Market Outlook
7.4 Market Breakup by Cell Culture
7.4.1 Mammalian Cell Culture
7.4.1.1 Key Market Drivers
7.4.1.2 Current and Historical Sales Trends
7.4.1.3 Current and Historical Manufacturing Capacity Trends
7.4.1.4 Market Breakup by Region
7.4.1.5 Market Breakup by Product Type
7.4.1.6 Key Players
7.4.1.7 Market Outlook
7.4.2 Microbial Cell Culture
7.4.2.1 Key Market Drivers
7.4.2.2 Current and Historical Sales Trends
7.4.2.3 Current and Historical Manufacturing Capacity Trends
7.4.2.4 Market Breakup by Product
7.4.2.5 Market Breakup by Region
7.4.2.6 Key Players
7.4.2.7 Market Outlook
7.5 Market Breakup by Class
7.5.1 Monoclonal Antibodies
7.5.1.1 Current and Historical Sales Trends
7.5.1.2 Market Outlook
7.5.2 Recombinant Proteins
7.5.2.1 Current and Historical Sales Trends
7.5.2.2 Market Outlook
7.5.3 Interferon
7.5.3.1 Current and Historical Sales Trends
7.5.3.2 Market Outlook
7.5.4 Granulocyte Colony-Stimulating Factor (G-CSF)
7.5.4.1 Current and Historical Sales Trends
7.5.4.2 Market Outlook
7.5.5 Erythropoietin
7.5.5.1 Current and Historical Sales Trends
7.5.5.2 Market Outlook
7.5.6 Recombinant Human Insulin
7.5.6.1 Current and Historical Sales Trends
7.5.6.2 Market Outlook
7.5.7 Vaccines
7.5.7.1 Current and Historical Sales Trends
7.5.7.2 Market Outlook
7.5.8 Human Growth Hormones (HGH)
7.5.8.1 Current and Historical Sales Trends
7.5.8.2 Market Outlook
7.6 Market Outlook
8 Competitive Landscape
8.1 Market Breakup by Manufacturer Type
8.1.1 Product Companies
8.1.2 Contract Manufacturers
8.2 Key Player Profiles
8.2.1 AbbVie Inc.
8.2.1.1 Company Overview
8.2.1.2 Key Financials
8.2.2 Amgen Inc.
8.2.2.1 Company Overview
8.2.2.2 Key Financials
8.2.3 Biogen Inc.
8.2.3.1 Company Overview
8.2.3.2 Key Financials
8.2.4 Eli Lilly and Company
8.2.4.1 Company Overview
8.2.4.2 Key Financials
8.2.5 F. Hoffmann-La Roche Ltd.
8.2.5.1 Company Overview
8.2.5.2 Key Financials
8.2.6 Johnson & Johnson Services Inc.
8.2.6.1 Company Overview
8.2.6.2 Key Financials
8.2.7 Merck & Co. Inc.
8.2.7.1 Company Overview
8.2.7.2 Key Financials
8.2.8 Novo Nordisk A/S
8.2.8.1 Company Overview
8.2.8.2 Key Financials
8.2.9 Pfizer Inc.
8.2.9.1 Company Overview
8.2.9.2 Key Financials
8.2.10 Sanofi S.A.
8.2.10.1 Company Overview
8.2.10.2 Key Financials
List of Figures
Figure 4-1: Global: Companies Manufacturing or Developing Active Substances for Follow-on Biologics (in no’s)
Figure 4-2: Global: Biopharmaceutical Products: Distribution by Production Technology (in no’s)
Figure 4-3: Global: Biopharmaceuticals: Mergers and Acquisitions Transaction Value (in US$ Billion)
Figure 4-4: Global: Orphan Drug Market: Designated vs Approvals (in no’s), 2018-2023
Figure 4-5: Global: Personalized Medicine Market (in US$ Billion), 2018 and 2023
Figure 4-6: Increase in Titers and Reduction in Capacity Utilization Rate (in %), 2018 and 2023
Figure 4-7: Disposable (Single Use) vs Stainless Steel Bioreactors
Figure 4-8: United States and Western Europe: Capacity Expansion
Figure 5-1: Global: Biopharmaceutical Market: Sales Trend (in US$ Billion), 2018-2023
Figure 5-2: Global: Biopharmaceutical Market: Breakup by Region (in %), 2023
Figure 5-3: Global: Biopharmaceutical Market: Breakup by Various Expression Systems (in %), 2023
Figure 5-4: Global: Biopharmaceutical Market: Expression Systems (Respondents’ Trends), 2018-2023
Figure 5-5: Global: Biopharmaceutical Market: Breakup by Drug Sales (in %), 2023
Figure 5-6: Global: Biopharmaceutical: Sales Trend Forecast (in US$ Billion), 2024-2032
Figure 5-7: Global: Biopharmaceutical Industry: SWOT Analysis
Figure 5-8: Global: Biopharmaceutical Industry: Value Chain Analysis
Figure 5-9: Global: Biopharmaceutical Industry: Porter’s Five Forces Analysis
Figure 6-1: United States: Biopharmaceutical Market: Sales Trend (in US$ Million), 2018-2023
Figure 6-2: United States: Biopharmaceutical Market: Sales Trend Forecast (in US$ Million), 2024-2032
Figure 6-3: Canada: Biopharmaceutical Market: Sales Trend (in US$ Million), 2018-2023
Figure 6-4: Canada: Biopharmaceutical Market: Sales Trend Forecast (in US$ Million), 2024-2032
Figure 6-5: United Kingdom: Biopharmaceutical Market: Sales Trend (in US$ Million), 2018-2023
Figure 6-6: United Kingdom: Biopharmaceutical Market: Sales Trend Forecast (in US$ Million), 2024-2032
Figure 6-7: Germany: Biopharmaceutical Market: Sales Trend (in US$ Million), 2018-2023
Figure 6-8: Germany: Biopharmaceutical Market: Sales Trend Forecast (in US$ Million), 2024-2032
Figure 6-9: France: Biopharmaceutical Market: Sales Trend (in Million US$), 2018-2023
Figure 6-10: France: Biopharmaceutical Market: Sales Trend Forecast (in Million US$), 2024-2032
Figure 6-11: Italy: Biopharmaceutical Market: Sales Trend (in US$ Million), 2018-2023
Figure 6-12: Italy: Biopharmaceutical Market: Sales Trend Forecast (in US$ Million), 2024-2032
Figure 6-13: Spain: Biopharmaceutical Market: Sales Trend (in US$ Million), 2018-2023
Figure 6-14: Spain: Biopharmaceutical Market: Sales Trend Forecast (in US$ Million), 2024-2032
Figure 6-15: Russia: Biopharmaceutical Market: Sales Trend (in US$ Million), 2018-2023
Figure 6-16: Russia: Biopharmaceutical Market: Sales Trend Forecast (in US$ Million), 2024-2032
Figure 6-17: Brazil: Biopharmaceutical Market: Sales Trend (in US$ Million), 2018-2023
Figure 6-18: Brazil: Biopharmaceutical Market: Sales Trend Forecast (in US$ Million), 2024-2032
Figure 6-19: Australia: Biopharmaceutical Market: Sales Trend (in US$ Million), 2018-2023
Figure 6-20: Australia: Biopharmaceutical Market: Sales Trend Forecast (in US$ Million), 2024-2032
Figure 7-1: Global: Biopharmaceutical Manufacturing: Capacity Trends (in Kilo Liters), 2018-2023
Figure 7-2: Global: Biopharmaceuticals Manufacturing: Capacity Breakup by Region (in %), 2023
Figure 7-3: North America: Biopharmaceuticals Manufacturing: Capacity Trend (in Kilo Liters), 2018-2023
Figure 7-4: North America: Biopharmaceuticals Manufacturing: Capacity Trend Forecast (in Kilo Liters), 2024-2032
Figure 7-5: Europe: Biopharmaceuticals Manufacturing: Capacity Trend (in Kilo Liters), 2018-2023
Figure 7-6: Europe: Biopharmaceuticals Manufacturing: Capacity Trend Forecast (in Kilo Liters), 2024-2032
Figure 7-7: Asia: Biopharmaceuticals Manufacturing: Capacity Trend (in Kilo Liters), 2018-2023
Figure 7-8: Asia: Biopharmaceuticals Manufacturing: Capacity Trend Forecast (in Kilo Liters), 2024-2032
Figure 7-9: Global: Mammalian Products: Sales Trend (in US$ Billion), 2018-2023
Figure 7-10: Global: Mammalian Cell Culture: Capacity Trend (in Kilo Liters), 2018-2023
Figure 7-11: Global: Mammalian Cell Culture: Capacity Utilization Trend (in %), 2018-2023
Figure 7-12: Global: Mammalian Cell Culture: Capacity Trends by Region (in Kilo Liters), 2018-2023
Figure 7-13: Global: Mammalian Cell Culture: Demand Breakup of Commercial Antibody Products (in %), 2023
Figure 7-14: Global: Mammalian Cell Culture: Market Breakup by Key Players (in %), 2023
Figure 7-15: Global: Mammalian Products: Sales Trend Forecast (in US$ Billion), 2024-2032
Figure 7-16: Global: Mammalian Cell Culture: Capacity Trend Forecast (in Kilo Liters), 2024-2032
Figure 7-17: Global: Mammalian Cell Culture: Capacity Trends Forecast by Region (in Kilo Liters), 2024-2032
Figure 7-18: Global: Microbial Products: Sales Trend (in US$ Billion), 2018-2023
Figure 7-19: Global: Microbial Cell Culture: Capacity Trend (in Kilo Liters), 2018-2023
Figure 7-20: Global: Microbial Cell Culture: Capacity (Commercial Volume) Trend (in Kilo Liters), 2018-2023
Figure 7-21: Global: Microbial Cell Culture: Capacity (Clinical Volume) Trend (in Kilo Liters), 2018-2023
Figure 7-22: Global: Microbial Cell Culture: Capacity Utilization Trend (in %), 2018-2023
Figure 7-23: Global: Microbial Cell Culture: Demand Breakup of Commercial Products (in %), 2023
Figure 7-24: Global: Microbial Cell Culture: Capacity (Commercial Volume) Trends by Region (in Kilo Liters), 2018-2023
Figure 7-25: Global: Microbial Cell Culture: Capacity (Clinical Volume) Trends by Region (in Kilo Liters), 2018-2023
Figure 7-26: Global: Microbial Cell Culture: Market Breakup by Key Players (in %), 2023
Figure 7-27: Global: Microbial Products: Sales Trend Forecast (in US$ Billion), 2024-2032
Figure 7-28: Global: Microbial Products: Capacity Trend Forecast (in Kilo Liters), 2024-2032
Figure 7-29: Global: Microbial Cell Culture: Capacity (Commercial Volume) Trends Forecast by Region (in Kilo Liters), 2024-2032
Figure 7-30: Global: Microbial Cell Culture: Capacity (Clinical Volume) Trends Forecast by Region (in Kilo Liters), 2024-2032
Figure 7-31: Global: Monoclonal Antibodies: Sales Trend (in US$ Billion), 2018-2023
Figure 7-32: Global: Monoclonal Antibodies: Sales Trend Forecast (in US$ Billion), 2024-2032
Figure 7-33: Global: Recombinant Proteins: Sales Trend (in US$ Billion), 2018-2023
Figure 7-34: Global: Recombinant Proteins: Sales Trend Forecast (in US$ Billion), 2024-2032
Figure 7-35: Global: Interferon: Sales Trend (in US$ Billion), 2018-2023
Figure 7-36: Global: Interferon: Sales Trend Forecast (in US$ Billion), 2024-2032
Figure 7-37: Global: Granulocyte Colony-Stimulating Factor (G-CSF): Sales Trend (in US$ Billion), 2018-2023
Figure 7-38: Global: Granulocyte Colony-Stimulating Factor (G-CSF): Sales Trend Forecast (in US$ Billion), 2024-2032
Figure 7-39: Global: Erythropoietin: Sales Trend (in US$ Billion), 2018-2023
Figure 7-40: Global: Erythropoietin: Sales Trend Forecast (in US$ Billion), 2024-2032
Figure 7-41: Global: Recombinant Human Insulin: Sales Trend (in US$ Billion), 2018-2023
Figure 7-42: Global: Recombinant Human Insulin: Sales Trend Forecast (in US$ Billion), 2024-2032
Figure 7-43: Global: Vaccines: Sales Trend (in US$ Billion), 2018-2023
Figure 7-44: Global: Vaccines: Sales Trend Forecast (in US$ Billion), 2024-2032
Figure 7-45: Global: Human Growth Hormones (HGH): Sales Trend (in US$ Billion), 2018-2023
Figure 7-46: Global: Human Growth Hormones (HGH): Sales Trend Forecast (in US$ Billion), 2024-2032
Figure 7-47: Global: Biopharmaceutical Manufacturing: Capacity Trend Forecast (In Kilo Liters), 2024-2032
Figure 8-1: Global: Biopharmaceutical Manufacturing: Capacity Breakup by Manufacturer Type (in %), 2023
Figure 8-2: Global: Biopharmaceutical Manufacturing: Capacity Breakup Forecast by Manufacturer Type (in %), 2032
Figure 8-3: Global: Biopharmaceutical Product Companies: Capacity Trend (in Kilo Liters), 2018-2023
Figure 8-4: Global: Biopharmaceutical Product Companies: Capacity Trend Forecast (in Kilo Liters), 2024-2032
Figure 8-5: Global: Biopharmaceutical CMOs: Capacity Trend (in Kilo Liters), 2018-2023
Figure 8-6: Global: Biopharmaceutical CMOs: Capacity Trend Forecast (in Kilo Liters), 2024-2032
Figure 8-7: AbbVie Inc.: Sales Value Trend (in Billion US$), 2014-2018
Figure 8-8: AbbVie Inc.: Revenue Breakup by Region (in %), 2019
Figure 8-9: Amgen Inc.: Sales Value Trend (in Billion USD), 2014-2018
Figure 8-10: Amgen Inc.: Revenue Breakup by Region (in %), 2019
Figure 8-11: Biogen Inc.: Sales Value Trend (in Billion USD), 2014-2018
Figure 8-12: Biogen Inc.: Revenue Breakup by Region (in %), 2019
Figure 8-13: Eli Lilly and Company: Sales Value Trend (in Billion USD), 2014-2018
Figure 8-14: Eli Lilly and Company: Revenue Breakup by Region (in %), 2019
Figure 8-15: F. Hoffmann-La Roche Ltd.: Sales Value Trend (in Billion USD), 2014-2018
Figure 8-16: F. Hoffmann-La Roche Ltd.: Revenue Breakup by Region (in %), 2019
Figure 8-17: Johnson & Johnson Services Inc.: Sales Value Trend (in Billion USD), 2014-2018
Figure 8-18: Johnson & Johnson Services Inc.: Revenue Breakup by Region (in %), 2019
Figure 8-19: Merck & Co. Inc.: Sales Value Trend (in Billion USD), 2014-2018
Figure 8-20: Merck & Co. Inc.: Revenue Breakup by Region (in %), 2019
Figure 8-21: Novo Nordisk A/S: Sales Value Trend (in Billion USD), 2014-2018
Figure 8-22: Novo Nordisk A/S: Revenue Breakup by Region (in %), 2019
Figure 8-23: Pfizer Inc.: Sales Value Trend (in Billion USD), 2014-2018
Figure 8-24: Pfizer Inc.: Revenue Breakup by Region (in %), 2019
Figure 8-25: Sanofi S.A.: Sales Value Trend (in Billion USD), 2014-2018
Figure 8-26: Sanofi S.A.: Revenue Breakup by Region (in %), 2019
List of Tables
Table 4-1: Global: Small Molecule Sales vs. Biopharmaceutical Sales (in Billion US$), 2018-2023
Table 8-1: AbbVie Inc.: Financial Data (2014-2018)
Table 8-2: Amgen Inc.: Financial Data (2014-2018)
Table 8-3: Biogen Inc.: Financial Data (2014-2018)
Table 8-4: Eli Lilly and Company: Financial Data (2014-2018)
Table 8-5: F. Hoffmann-La Roche Ltd.: Financial Data (2014-2018)
Table 8-6: Johnson & Johnson Services Inc.: Financial Data (2014-2018)
Table 8-7: Merck & Co. Inc.: Financial Data (2014-2018)
Table 8-8: Novo Nordisk A/S: Financial Data (2014-2018)
Table 8-9: Pfizer Inc.: Financial Data (2014-2018)
Table 8-10: Sanofi S.A.: Financial Data (2014-2018)