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Biopharmaceutical Manufacturing Market Report by Cell Culture (Mammalian Cell Culture, Microbial Cell Culture), Class (Monoclonal Antibodies, Recombinant Proteins, Interferon, Granulocyte Colony-Stimulating Factor (G-CSF), Erythropoietin, Recombinant Human Insulin, Vaccines, Human Growth Hormones (HGH)), and Region 2025-2033
Report Format: PDF+Excel | Report ID: SR112024A724
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1 Preface
2 Research Methodology and Market Definitions
3 Executive Summary
4 Global Biopharmaceutical Market: Key Trends
4.1 Biopharmaceuticals are Growing Faster than Small Molecule Drugs
4.2 Growth of Biosimilars will Push Volumes and Introduce New Players in this Market
4.3 A Rich Biopharmaceutical Pipeline will Drive the Capacity Demand in the Coming Years
4.4 Increasing Trends in Mergers and Acquisitions will Increase Redundant Capacities
4.5 Increasing Focus on Personalized Medicines and High Value Low Volume Markets
4.6 Higher Titers will Reduce Capacity Demand
4.7 Growth in the Use of Cost Effective Disposable Technologies
4.8 Despite Sufficient Global Capacity, Its Uneven Distribution will Continue to Spur Demand
5 Global Biopharmaceutical Market: Industry Performance
5.1 Current and Historical Sales Trends
5.2 Market Breakup by Region
5.3 Market Breakup by Expression Systems
5.4 Market Breakup by Product Type
5.5 Market Outlook
5.6 SWOT Analysis
5.6.1 Strengths
5.6.2 Weaknesses
5.6.3 Opportunities
5.6.4 Threats
5.7 Value Chain Analysis
5.8 Porter’s Five Forces Analysis
5.8.1 Overview
5.8.2 Bargaining Power of Buyers
5.8.3 Bargaining Power of Suppliers
5.8.4 Degree of Competition
5.8.5 Threat of New Entrants
5.8.6 Threat of Substitutes
6 Regional Biopharmaceutical Market Analysis
6.1 United States
6.1.1 Current and Historical Sales Trends
6.1.2 Market Outlook
6.2 Canada
6.2.1 Current and Historical Sales Trends
6.2.2 Market Outlook
6.3 United Kingdom
6.3.1 Current and Historical Sales Trends
6.3.2 Market Outlook
6.4 Germany
6.4.1 Current and Historical Sales Trends
6.4.2 Market Outlook
6.5 France
6.5.1 Current and Historical Sales Trends
6.5.2 Market Outlook
6.6 Italy
6.6.1 Current and Historical Sales Trends
6.6.2 Market Outlook
6.7 Spain
6.7.1 Current and Historical Sales Trends
6.7.2 Market Outlook
6.8 Russia
6.8.1 Current and Historical Sales Trends
6.8.2 Market Outlook
6.9 Brazil
6.9.1 Current and Historical Sales Trends
6.9.2 Market Outlook
6.10 Australia
6.10.1 Current and Historical Sales Trends
6.10.2 Market Outlook
7 Global Biopharmaceutical Manufacturing Industry
7.1 Current and Historical Manufacturing Capacity Trends
7.2 Impact of COVID-19
7.3 Market Breakup by Region
7.3.1 North America
7.3.1.1 Current and Historical Manufacturing Capacity Trends
7.3.1.2 Market Outlook
7.3.2 Europe
7.3.2.1 Current and Historical Manufacturing Capacity Trends
7.3.2.2 Market Outlook
7.3.3 Asia
7.3.3.1 Current and Historical Manufacturing Capacity Trends
7.3.3.2 Market Outlook
7.4 Market Breakup by Cell Culture
7.4.1 Mammalian Cell Culture
7.4.1.1 Key Market Drivers
7.4.1.2 Current and Historical Sales Trends
7.4.1.3 Current and Historical Manufacturing Capacity Trends
7.4.1.4 Market Breakup by Region
7.4.1.5 Market Breakup by Product Type
7.4.1.6 Key Players
7.4.1.7 Market Outlook
7.4.2 Microbial Cell Culture
7.4.2.1 Key Market Drivers
7.4.2.2 Current and Historical Sales Trends
7.4.2.3 Current and Historical Manufacturing Capacity Trends
7.4.2.4 Market Breakup by Product
7.4.2.5 Market Breakup by Region
7.4.2.6 Key Players
7.4.2.7 Market Outlook
7.5 Market Breakup by Class
7.5.1 Monoclonal Antibodies
7.5.1.1 Current and Historical Sales Trends
7.5.1.2 Market Outlook
7.5.2 Recombinant Proteins
7.5.2.1 Current and Historical Sales Trends
7.5.2.2 Market Outlook
7.5.3 Interferon
7.5.3.1 Current and Historical Sales Trends
7.5.3.2 Market Outlook
7.5.4 Granulocyte Colony-Stimulating Factor (G-CSF)
7.5.4.1 Current and Historical Sales Trends
7.5.4.2 Market Outlook
7.5.5 Erythropoietin
7.5.5.1 Current and Historical Sales Trends
7.5.5.2 Market Outlook
7.5.6 Recombinant Human Insulin
7.5.6.1 Current and Historical Sales Trends
7.5.6.2 Market Outlook
7.5.7 Vaccines
7.5.7.1 Current and Historical Sales Trends
7.5.7.2 Market Outlook
7.5.8 Human Growth Hormones (HGH)
7.5.8.1 Current and Historical Sales Trends
7.5.8.2 Market Outlook
7.6 Market Outlook
8 Competitive Landscape
8.1 Market Breakup by Manufacturer Type
8.1.1 Product Companies
8.1.2 Contract Manufacturers
8.2 Key Player Profiles
8.2.1 AbbVie Inc.
8.2.1.1 Company Overview
8.2.1.2 Key Financials
8.2.2 Amgen Inc.
8.2.2.1 Company Overview
8.2.2.2 Key Financials
8.2.3 Biogen Inc.
8.2.3.1 Company Overview
8.2.3.2 Key Financials
8.2.4 Eli Lilly and Company
8.2.4.1 Company Overview
8.2.4.2 Key Financials
8.2.5 F. Hoffmann-La Roche Ltd.
8.2.5.1 Company Overview
8.2.5.2 Key Financials
8.2.6 Johnson & Johnson Services Inc.
8.2.6.1 Company Overview
8.2.6.2 Key Financials
8.2.7 Merck & Co. Inc.
8.2.7.1 Company Overview
8.2.7.2 Key Financials
8.2.8 Novo Nordisk A/S
8.2.8.1 Company Overview
8.2.8.2 Key Financials
8.2.9 Pfizer Inc.
8.2.9.1 Company Overview
8.2.9.2 Key Financials
8.2.10 Sanofi S.A.
8.2.10.1 Company Overview
8.2.10.2 Key Financials
List of Figures
Figure 4-1: Global: Companies Manufacturing or Developing Active Substances for Follow-on Biologics (in no’s)
Figure 4-2: Global: Biopharmaceutical Products: Distribution by Production Technology (in no’s)
Figure 4-3: Global: Biopharmaceuticals: Mergers and Acquisitions Transaction Value (in USD Billion)
Figure 4-4: Global: Orphan Drug Market: Designated vs Approvals (in no’s), 2019-2024
Figure 4-5: Global: Personalized Medicine Market (in USD Billion), 2019 & 2024
Figure 4-6: Increase in Titers and Reduction in Capacity Utilization Rate (in %), 2019 & 2024
Figure 4-7: Disposable (Single Use) vs Stainless Steel Bioreactors
Figure 4-8: United States and Western Europe: Capacity Expansion
Figure 5-1: Global: Biopharmaceutical Market: Sales Trend (in USD Billion), 2019-2024
Figure 5-2: Global: Biopharmaceutical Market: Breakup by Region (in %), 2024
Figure 5-3: Global: Biopharmaceutical Market: Breakup by Various Expression Systems (in %), 2024
Figure 5-4: Global: Biopharmaceutical Market: Expression Systems (Respondents’ Trends), 2019-2024
Figure 5-5: Global: Biopharmaceutical Market: Breakup by Drug Sales (in %), 2024
Figure 5-6: Global: Biopharmaceutical: Sales Trend Forecast (in USD Billion), 2025-2033
Figure 5-7: Global: Biopharmaceutical Industry: SWOT Analysis
Figure 5-8: Global: Biopharmaceutical Industry: Value Chain Analysis
Figure 5-9: Global: Biopharmaceutical Industry: Porter’s Five Forces Analysis
Figure 6-1: United States: Biopharmaceutical Market: Sales Trend (in USD Million), 2019-2024
Figure 6-2: United States: Biopharmaceutical Market: Sales Trend Forecast (in USD Million), 2025-2033
Figure 6-3: Canada: Biopharmaceutical Market: Sales Trend (in USD Million), 2019-2024
Figure 6-4: Canada: Biopharmaceutical Market: Sales Trend Forecast (in USD Million), 2025-2033
Figure 6-5: United Kingdom: Biopharmaceutical Market: Sales Trend (in USD Million), 2019-2024
Figure 6-6: United Kingdom: Biopharmaceutical Market: Sales Trend Forecast (in USD Million), 2025-2033
Figure 6-7: Germany: Biopharmaceutical Market: Sales Trend (in USD Million), 2019-2024
Figure 6-8: Germany: Biopharmaceutical Market: Sales Trend Forecast (in USD Million), 2025-2033
Figure 6-9: France: Biopharmaceutical Market: Sales Trend (in Million USD), 2019-2024
Figure 6-10: France: Biopharmaceutical Market: Sales Trend Forecast (in Million USD), 2025-2033
Figure 6-11: Italy: Biopharmaceutical Market: Sales Trend (in USD Million), 2019-2024
Figure 6-12: Italy: Biopharmaceutical Market: Sales Trend Forecast (in USD Million), 2025-2033
Figure 6-13: Spain: Biopharmaceutical Market: Sales Trend (in USD Million), 2019-2024
Figure 6-14: Spain: Biopharmaceutical Market: Sales Trend Forecast (in USD Million), 2025-2033
Figure 6-15: Russia: Biopharmaceutical Market: Sales Trend (in USD Million), 2019-2024
Figure 6-16: Russia: Biopharmaceutical Market: Sales Trend Forecast (in USD Million), 2025-2033
Figure 6-17: Brazil: Biopharmaceutical Market: Sales Trend (in USD Million), 2019-2024
Figure 6-18: Brazil: Biopharmaceutical Market: Sales Trend Forecast (in USD Million), 2025-2033
Figure 6-19: Australia: Biopharmaceutical Market: Sales Trend (in USD Million), 2019-2024
Figure 6-20: Australia: Biopharmaceutical Market: Sales Trend Forecast (in USD Million), 2025-2033
Figure 7-1: Global: Biopharmaceutical Manufacturing: Capacity Trends (in Kilo Liters), 2019-2024
Figure 7-2: Global: Biopharmaceuticals Manufacturing: Capacity Breakup by Region (in %), 2024
Figure 7-3: North America: Biopharmaceuticals Manufacturing: Capacity Trend (in Kilo Liters), 2019-2024
Figure 7-4: North America: Biopharmaceuticals Manufacturing: Capacity Trend Forecast (in Kilo Liters), 2025-2033
Figure 7-5: Europe: Biopharmaceuticals Manufacturing: Capacity Trend (in Kilo Liters), 2019-2024
Figure 7-6: Europe: Biopharmaceuticals Manufacturing: Capacity Trend Forecast (in Kilo Liters), 2025-2033
Figure 7-7: Asia: Biopharmaceuticals Manufacturing: Capacity Trend (in Kilo Liters), 2019-2024
Figure 7-8: Asia: Biopharmaceuticals Manufacturing: Capacity Trend Forecast (in Kilo Liters), 2025-2033
Figure 7-9: Global: Mammalian Products: Sales Trend (in USD Billion), 2019-2024
Figure 7-10: Global: Mammalian Cell Culture: Capacity Trend (in Kilo Liters), 2019-2024
Figure 7-11: Global: Mammalian Cell Culture: Capacity Utilization Trend (in %), 2019-2024
Figure 7-12: Global: Mammalian Cell Culture: Capacity Trends by Region (in Kilo Liters), 2019-2024
Figure 7-13: Global: Mammalian Cell Culture: Demand Breakup of Commercial Antibody Products (in %), 2024
Figure 7-14: Global: Mammalian Cell Culture: Market Breakup by Key Players (in %), 2024
Figure 7-15: Global: Mammalian Products: Sales Trend Forecast (in USD Billion), 2025-2033
Figure 7-16: Global: Mammalian Cell Culture: Capacity Trend Forecast (in Kilo Liters), 2025-2033
Figure 7-17: Global: Mammalian Cell Culture: Capacity Trends Forecast by Region (in Kilo Liters), 2025-2033
Figure 7-18: Global: Microbial Products: Sales Trend (in USD Billion), 2019-2024
Figure 7-19: Global: Microbial Cell Culture: Capacity Trend (in Kilo Liters), 2019-2024
Figure 7-20: Global: Microbial Cell Culture: Capacity (Commercial Volume) Trend (in Kilo Liters), 2019-2024
Figure 7-21: Global: Microbial Cell Culture: Capacity (Clinical Volume) Trend (in Kilo Liters), 2019-2024
Figure 7-22: Global: Microbial Cell Culture: Capacity Utilization Trend (in %), 2019-2024
Figure 7-23: Global: Microbial Cell Culture: Demand Breakup of Commercial Products (in %), 2024
Figure 7-24: Global: Microbial Cell Culture: Capacity (Commercial Volume) Trends by Region (in Kilo Liters), 2019-2024
Figure 7-25: Global: Microbial Cell Culture: Capacity (Clinical Volume) Trends by Region (in Kilo Liters), 2019-2024
Figure 7-26: Global: Microbial Cell Culture: Market Breakup by Key Players (in %), 2024
Figure 7-27: Global: Microbial Products: Sales Trend Forecast (in USD Billion), 2025-2033
Figure 7-28: Global: Microbial Products: Capacity Trend Forecast (in Kilo Liters), 2025-2033
Figure 7-29: Global: Microbial Cell Culture: Capacity (Commercial Volume) Trends Forecast by Region (in Kilo Liters), 2025-2033
Figure 7-30: Global: Microbial Cell Culture: Capacity (Clinical Volume) Trends Forecast by Region (in Kilo Liters), 2025-2033
Figure 7-31: Global: Monoclonal Antibodies: Sales Trend (in USD Billion), 2019-2024
Figure 7-32: Global: Monoclonal Antibodies: Sales Trend Forecast (in USD Billion), 2025-2033
Figure 7-33: Global: Recombinant Proteins: Sales Trend (in USD Billion), 2019-2024
Figure 7-34: Global: Recombinant Proteins: Sales Trend Forecast (in USD Billion), 2025-2033
Figure 7-35: Global: Interferon: Sales Trend (in USD Billion), 2019-2024
Figure 7-36: Global: Interferon: Sales Trend Forecast (in USD Billion), 2025-2033
Figure 7-37: Global: Granulocyte Colony-Stimulating Factor (G-CSF): Sales Trend (in USD Billion), 2019-2024
Figure 7-38: Global: Granulocyte Colony-Stimulating Factor (G-CSF): Sales Trend Forecast (in USD Billion), 2025-2033
Figure 7-39: Global: Erythropoietin: Sales Trend (in USD Billion), 2019-2024
Figure 7-40: Global: Erythropoietin: Sales Trend Forecast (in USD Billion), 2025-2033
Figure 7-41: Global: Recombinant Human Insulin: Sales Trend (in USD Billion), 2019-2024
Figure 7-42: Global: Recombinant Human Insulin: Sales Trend Forecast (in USD Billion), 2025-2033
Figure 7-43: Global: Vaccines: Sales Trend (in USD Billion), 2019-2024
Figure 7-44: Global: Vaccines: Sales Trend Forecast (in USD Billion), 2025-2033
Figure 7-45: Global: Human Growth Hormones (HGH): Sales Trend (in USD Billion), 2019-2024
Figure 7-46: Global: Human Growth Hormones (HGH): Sales Trend Forecast (in USD Billion), 2025-2033
Figure 7-47: Global: Biopharmaceutical Manufacturing: Capacity Trend Forecast (In Kilo Liters), 2025-2033
Figure 8-1: Global: Biopharmaceutical Manufacturing: Capacity Breakup by Manufacturer Type (in %), 2024
Figure 8-2: Global: Biopharmaceutical Manufacturing: Capacity Breakup Forecast by Manufacturer Type (in %), 2033
Figure 8-3: Global: Biopharmaceutical Product Companies: Capacity Trend (in Kilo Liters), 2019-2024
Figure 8-4: Global: Biopharmaceutical Product Companies: Capacity Trend Forecast (in Kilo Liters), 2025-2033
Figure 8-5: Global: Biopharmaceutical CMOs: Capacity Trend (in Kilo Liters), 2019-2024
Figure 8-6: Global: Biopharmaceutical CMOs: Capacity Trend Forecast (in Kilo Liters), 2025-2033
Figure 8-7: AbbVie Inc.: Sales Value Trend (in Billion USD), 2015-2019
Figure 8-8: AbbVie Inc.: Revenue Breakup by Region (in %), 2020
Figure 8-9: Amgen Inc.: Sales Value Trend (in Billion USD), 2015-2019
Figure 8-10: Amgen Inc.: Revenue Breakup by Region (in %), 2020
Figure 8-11: Biogen Inc.: Sales Value Trend (in Billion USD), 2015-2019
Figure 8-12: Biogen Inc.: Revenue Breakup by Region (in %), 2020
Figure 8-13: Eli Lilly and Company: Sales Value Trend (in Billion USD), 2015-2019
Figure 8-14: Eli Lilly and Company: Revenue Breakup by Region (in %), 2020
Figure 8-15: F. Hoffmann-La Roche Ltd.: Sales Value Trend (in Billion USD), 2015-2019
Figure 8-16: F. Hoffmann-La Roche Ltd.: Revenue Breakup by Region (in %), 2020
Figure 8-17: Johnson & Johnson Services Inc.: Sales Value Trend (in Billion USD), 2015-2019
Figure 8-18: Johnson & Johnson Services Inc.: Revenue Breakup by Region (in %), 2020
Figure 8-19: Merck & Co. Inc.: Sales Value Trend (in Billion USD), 2015-2019
Figure 8-20: Merck & Co. Inc.: Revenue Breakup by Region (in %), 2020
Figure 8-21: Novo Nordisk A/S: Sales Value Trend (in Billion USD), 2015-2019
Figure 8-22: Novo Nordisk A/S: Revenue Breakup by Region (in %), 2020
Figure 8-23: Pfizer Inc.: Sales Value Trend (in Billion USD), 2015-2019
Figure 8-24: Pfizer Inc.: Revenue Breakup by Region (in %), 2020
Figure 8-25: Sanofi S.A.: Sales Value Trend (in Billion USD), 2015-2019
Figure 8-26: Sanofi S.A.: Revenue Breakup by Region (in %), 2020
List of Tables
Table 4-1: Global: Small Molecule Sales vs. Biopharmaceutical Sales (in Billion USD), 2019-2024
Table 8-1: AbbVie Inc.: Financial Data (2015-2019)
Table 8-2: Amgen Inc.: Financial Data (2015-2019)
Table 8-3: Biogen Inc.: Financial Data (2015-2019)
Table 8-4: Eli Lilly and Company: Financial Data (2015-2019)
Table 8-5: F. Hoffmann-La Roche Ltd.: Financial Data (2015-2019)
Table 8-6: Johnson & Johnson Services Inc.: Financial Data (2015-2019)
Table 8-7: Merck & Co. Inc.: Financial Data (2015-2019)
Table 8-8: Novo Nordisk A/S: Financial Data (2015-2019)
Table 8-9: Pfizer Inc.: Financial Data (2015-2019)
Table 8-10: Sanofi S.A.: Financial Data (2015-2019)
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