Postoperative Pain Therapeutics Market

Market Overview:

The global postoperative pain therapeutics market size reached USD 14.7 Billion in 2024. Looking forward, IMARC Group expects the market to reach USD 23.0 Billion by 2033, exhibiting a growth rate (CAGR) of 5.19% during 2025-2033. The increasing number of orthopedic surgeries, improving healthcare infrastructure, and extensive research and development (R&D) activities represent some of the key factors driving the market.

Postoperative pain therapeutics refers to the various methods and medications used to reduce or eliminate pain and discomfort with minimal side effects. They include pain relievers, opioids, non-steroidal anti-inflammatory drugs (NSAIDs), local anesthetics, tricyclic antidepressants, and antiepileptic drugs. These medications provide relief from the distressing feeling caused due to postsurgical pain. Postoperative pain therapeutics are widely used to promote relaxation, reduce surgical stress, and improve overall patient outcomes. They are commonly administered to patients through oral, intravenous, and intramuscular routes. Postoperative pain therapeutics help patients feel comfortable, recover more quickly, and avoid adverse effects, such as prolonged pain and hospitalization, or risk of addiction to pain medications. They also assist in expediting the recovery process and reducing the chances of complications, such as pneumonia and blood clots.

Postoperative Pain Therapeutics Market Trends:

The growing number of surgical procedures due to the rising prevalence of chronic diseases across the globe is one of the key factors driving the market growth. Postoperative pain therapeutics are widely used in phantom pain condition that occurs after thoracotomy, breast surgery, limb amputation, cesarean section, or inguinal hernia repair. In line with this, the widespread product adoption to manage heavy pain and soreness due to the increasing cases of road accidents and relative trauma injuries is favoring the market growth. Apart from this, key players are focusing on the development of postoperative pain therapeutics that are safer, more effective, economically viable, and easier to administer, which in turn is providing an impetus to the market growth. Moreover, the increasing adoption of the oral route of administration owing to its high preference for non-invasiveness, ease of use, and self-administration characteristics is acting as another growth-inducing factor. Additionally, the rising demand for NSAIDs to relieve pain, reduce inflammation, and bring down high body temperatures is propelling the market growth. Furthermore, the growing focus on improving patient experience and satisfaction and increasing awareness of adequate pain management is positively influencing the market growth. Other factors, including the increasing number of orthopedic surgeries, improving healthcare infrastructure, extensive research and development (R&D) activities, rising development and commercialization of non-narcotic drugs, and supportive government policies for novel drug discovery, are creating a positive outlook for the market.

Key Market Segmentation:

IMARC Group provides an analysis of the key trends in each segment of the global postoperative pain therapeutics market report, along with forecasts at the global, regional, and country levels for 2025-2033. Our report has categorized the market based on drug class, route of administration, and distribution channel.

Drug Class Insights:

• Opioids
• NSAIDs
• Local Anesthetics
• Tricyclic Antidepressants
• Antiepileptic Drugs
• Others
   

The report has provided a detailed breakup and analysis of the postoperative pain therapeutics market based on the drug class. This includes opioids, NSAIDs, local anesthetics, tricyclic antidepressants, antiepileptic drugs, and others. According to the report, opioids represented the largest segment.

Route of Administration Insights:

• Oral
• Intravenous
• Intramuscular
• Others
   

A detailed breakup and analysis of the postoperative pain therapeutics market based on the route of administration has also been provided in the report. This includes oral, intravenous, intramuscular, and others. According to the report, oral accounted for the largest market share.

Distribution Channel Insights:

• Hospital Pharmacies
• Retail Pharmacies
• Online Pharmacies
• Others
   

The report has provided a detailed breakup and analysis of the postoperative pain therapeutics market based on the distribution channel. This includes hospital pharmacies, retail pharmacies, online pharmacies, and others. According to the report, hospital pharmacies represented the largest segment.

Regional Insights:

• North America
  • United States
  • Canada
• Europe
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Others
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Indonesia
  • Others
• Latin America
  • Brazil
  • Mexico
  • Others
• Middle East and Africa
   

The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America was the largest market for postoperative pain therapeutics. Some of the factors driving the North America postoperative pain therapeutics market included the growing number of surgical procedures, extensive research and development (R&D) activities, and significant technological advancements.

Competitive Landscape:

The report has also provided a comprehensive analysis of the competitive landscape in the global postoperative pain therapeutics market. Competitive analysis such as market structure, market share by key players, player positioning, top winning strategies, competitive dashboard, and company evaluation quadrant has been covered in the report. Also, detailed profiles of all major companies have been provided. Some of the companies covered include Heron Therapeutics, Mallinckrodt Pharmaceuticals, Pacira BioSciences, Inc., Pfizer, Inc., Trevena, Inc., etc. Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.

Postoperative Pain Therapeutics Market Report Scope:

Key Questions Answered in This Report:

• How has the global postoperative pain therapeutics market performed so far, and how will it perform in the coming years?
• What are the drivers, restraints, and opportunities in the global postoperative pain therapeutics market?
• What is the impact of each driver, restraint, and opportunity on the global postoperative pain therapeutics market?
• What are the key regional markets?
• Which countries represent the most attractive postoperative pain therapeutics market?
• What is the breakup of the market based on the drug class?
• Which is the most attractive drug class in the postoperative pain therapeutics market?
• What is the breakup of the market based on the route of administration?
• Which is the most attractive route of administration in the postoperative pain therapeutics market?
• What is the breakup of the market based on the distribution channel?
• Which is the most attractive distribution channel in the postoperative pain therapeutics market?
• What is the competitive structure of the global postoperative pain therapeutics market?
• Who are the key players/companies in the global postoperative pain therapeutics market?

Key Benefits for Stakeholders:

• IMARC’s report offers a comprehensive quantitative analysis of various market segments, historical and current market trends, market forecasts, and dynamics of the postoperative pain therapeutics market from 2019-2033.
• The research study provides the latest information on the market drivers, challenges, and opportunities in the global postoperative pain therapeutics market.
• The study maps the leading, as well as the fastest-growing, regional markets. It further enables stakeholders to identify the key country-level markets within each region.
• Porter's five forces analysis assist stakeholders in assessing the impact of new entrants, competitive rivalry, supplier power, buyer power, and the threat of substitution. It helps stakeholders to analyze the level of competition within the postoperative pain therapeutics industry and its attractiveness.
• Competitive landscape allows stakeholders to understand their competitive environment and provides an insight into the current positions of key players in the market.