The 7 major hyperlipoproteinemia type II markets are expected to exhibit a CAGR of 6.79% during 2024-2034.
Report Attribute
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Key Statistics
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Base Year
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2023
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Forecast Years
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2024-2034
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Historical Years
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2018-2023
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Market Growth Rate 2024-2034 | 6.79% |
The hyperlipoproteinemia type II market has been comprehensively analyzed in IMARC's new report titled "Hyperlipoproteinemia Type II Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Hyperlipoproteinemia type II, also known as familial hypercholesterolemia (FH), is a genetic condition characterized by high cholesterol concentrations, specifically elevated levels of low-density lipoprotein (LDL), often referred to as bad cholesterol. The most typical symptom of this illness includes yellowish, raised nodules under the skin, particularly around the eyes, elbows, knees, and tendons. Additionally, individuals suffering from the ailment have a significantly higher risk of developing premature coronary artery disease, heart attacks, and strokes. In some cases, hyperlipoproteinemia type II can lead to clouding of the cornea, affecting the vision. The diagnosis of this condition is usually made through a combination of clinical evaluation, review of personal and family medical history, and lipid profile analysis. The healthcare provider may perform a physical examination to assess any signs of FH, such as fatty deposits under the skin or around the eyes. Genetic testing may also be used to confirm the diagnosis and identify specific gene mutations associated with the disease. Numerous other investigations, like electrocardiograms, echocardiography, stress tests, etc., might be required to evaluate the extent of cardiovascular risk in patients.
The rising cases of genetic mutations, which can affect the body's ability to efficiently remove LDL cholesterol from the blood, thereby leading to its accumulation, are primarily driving the hyperlipoproteinemia type II market. In addition to this, the increasing incidence of various associated risk factors, including obesity, sedentary lifestyle, consumption of a diet high in saturated and trans fats, metabolic syndrome, etc., is creating a positive outlook for the market. Moreover, the widespread adoption of effective medications, such as atorvastatin, simvastatin, rosuvastatin, etc., since they work by blocking an enzyme responsible for cholesterol synthesis in the liver, leading to a reduction in LDL levels, is further bolstering the market growth. Apart from this, the inflating popularity of apheresis procedures owing to their numerous advantages, like symptom relief, improved quality of life, and reduced cardiovascular risk, is acting as another significant growth-inducing factor. Additionally, the emerging application of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors via subcutaneous injections to enhance treatment adherence compared to several other injectable medications is expected to drive the hyperlipoproteinemia type II market during the forecast period.
IMARC Group's new report provides an exhaustive analysis of the hyperlipoproteinemia type II market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for hyperlipoproteinemia type II and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the hyperlipoproteinemia type II market in any manner.
Time Period of the Study
Countries Covered
Analysis Covered Across Each Country
This report also provides a detailed analysis of the current hyperlipoproteinemia type II marketed drugs and late-stage pipeline drugs.
In-Market Drugs
Late-Stage Pipeline Drugs
Drugs | Company Name |
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Atorvastatin calcium suspension (ATORVALIQ) | CMP Pharma |
MK-733 (Simvastatin) | Merck & Co |
Evinacumab | Regeneron Pharmaceuticals |
MGL-3196 (Resmetirom) | Madrigal Pharmaceuticals |
MBX 8025 (Seladelpar) | CymaBay Therapeutics |
*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.
Market Insights
Epidemiology Insights
Hyperlipoproteinemia Type II: Current Treatment Scenario, Marketed Drugs and Emerging Therapies