The 7 major hereditary central nervous system demyelinating diseases markets are expected to exhibit a CAGR of 9.65% during 2024-2034.
Report Attribute
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Key Statistics
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Base Year
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2023
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Forecast Years
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2024-2034
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Historical Years
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2018-2023
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Market Growth Rate 2024-2034 | 9.65% |
The hereditary central nervous system demyelinating diseases market has been comprehensively analyzed in IMARC's new report titled "Hereditary Central Nervous System Demyelinating Diseases Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Hereditary central nervous system demyelinating diseases (HCNSDD) comprise a group of rare inherited disorders characterized by the progressive loss of myelin, the protective sheath that covers nerve fibers in the central nervous system (CNS). Myelin facilitates efficient nerve signal transmission, and its deterioration results in a range of neurological symptoms. Common indications of HCNSDD encompass a variety of motor and sensory impairments, including muscle weakness, poor coordination, tremors, and difficulty walking. In some cases, cognitive and visual disturbances, as well as speech and swallowing difficulties, may also manifest. Since these diseases have a genetic basis, patients may present with symptoms at different ages, with severity varying from mild to debilitating. Diagnosing HCNSDD involves a combination of clinical evaluation, neuroimaging techniques like magnetic resonance imaging (MRI), and genetic testing. MRI scans often reveal characteristic patterns of demyelination and atrophy within the CNS. Genetic testing identifies mutations in specific genes associated with these disorders, aiding in accurate diagnosis and classification.
The escalating cases of mutations in specific genes, which can affect proteins involved in myelin production, maintenance, or the regulation of the immune response, are primarily driving the hereditary central nervous system demyelinating diseases market. In addition to this, the inflating utilization of targeted pharmaceutical treatments, including enzyme replacement therapies and immunomodulatory agents, that aim to alleviate symptoms and decelerate the progression of the ailment in patients is also creating a positive outlook for the market. Moreover, the widespread adoption of advanced diagnostic modalities like next-generation sequencing for enhancing the early detection and understanding of these disorders is further bolstering the market growth. Apart from this, the rising usage of rehabilitative measures, such as physical therapy and occupational therapy, is acting as another significant growth-inducing factor. These therapies are crucial in maintaining functional independence and improving the quality of life by focusing on mobility, fine motor skills, and adaptive strategies. Additionally, the increasing research initiatives surrounding gene therapy, since it can help to replace or repair the defective genes that cause the loss of myelin in individuals suffering from HCNSDD, are expected to drive the hereditary central nervous system demyelinating diseases market during the forecast period.
IMARC Group's new report provides an exhaustive analysis of the hereditary central nervous system demyelinating diseases market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for hereditary central nervous system demyelinating diseases and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the hereditary central nervous system demyelinating diseases market in any manner.
Time Period of the Study
Countries Covered
Analysis Covered Across Each Country
This report also provides a detailed analysis of the current hereditary central nervous system demyelinating diseases marketed drugs and late-stage pipeline drugs.
In-Market Drugs
Late-Stage Pipeline Drugs
Drugs | Company Name |
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Libmeldy (Atidarsagene autotemcel) | Orchard Therapeutics |
FBX-101 | Forge Biologics |
AAV9 BBP-812 | Aspa Therapeutics |
rAAV-Olig001-ASPA | Myrtelle |
ION373 | Ionis Pharmaceuticals |
Leriglitazone | Minoryx Therapeutics |
*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.
Market Insights
Epidemiology Insights
Hereditary Central Nervous System Demyelinating Diseases: Current Treatment Scenario, Marketed Drugs and Emerging Therapies