Gene Synthesis Market

Market Overview:

The global gene synthesis market size reached USD 2.1 Billion in 2023. Looking forward, IMARC Group expects the market to reach USD 8.3 Billion by 2032, exhibiting a growth rate (CAGR) of 16.58% during 2024-2032. The rising prevalence of various genetic disorders, increasing preference for gene therapeutics and personalized medicine, and inflating disposable income levels represent some of the key factors supporting the market growth.

Gene synthesis is an important tool for genetic engineering, which is the process by which nucleotides are assembled in a specific order in a laboratory setting in order to create desired sequences of DNA. This technology allows researchers to create DNA sequences tailored to their specific research needs, and the DNA can be scaled up for larger quantities of use in experiments or production processes. In the case of large and complex DNA sequences, gene synthesis can take only a few days or weeks with error rates approaching 1 per 10,000 bases. It is possible to introduce specific mutations into existing genes as well as create DNA fragments that can then be cloned and expressed, creating synthetic genes that encode proteins with specific characteristics, such as enhanced stability or activity.

Gene Synthesis Market Trends: 

Increasing demand for synthetic biology

Synthetic biology permits the creation of new biological components, technologies, and systems. This skill is crucial for creating novel medicines, such as gene therapies and biopharmaceuticals, which require accurate gene synthesis to produce specific DNA sequences. The new focus on vaccine research is underlining the significance of synthetic biology. Gene synthesis is essential in the design and production of antigens and other vaccine components, resulting in rising demand for these services. Synthetic biology is the process of genetically modifying organisms, which is expanding the gene synthesis market scope. This involves the creation of unique genes for a variety of uses, including research, agriculture, and pharmaceuticals. The advent of synthetic biology in biomanufacturing, where microbes are modified to create valuable chemicals such as enzymes, biofuels, and medications, necessitates extensive gene synthesis. Companies are using synthetic biology to improve manufacturing efficiency and lower costs.

Advancements in biotechnology

Innovations in DNA synthesis technology, such as microfluidics and high-throughput sequencing, are improving gene synthesis speed, accuracy, and cost-effectiveness. These advancements make it easier for scientists and businesses to obtain bespoke genes customized to their specific requirements. The advent of NGS technologies is transforming genomics, allowing for quick and thorough gene synthesis market analysis of genetic data. This rise in sequencing data necessitates matching synthetic genes for research and therapeutic applications, resulting in increased demand for gene synthesis services. As researchers use these methods for genetic engineering, they rely more on synthesized genes to make precise changes, increasing the requirement for gene synthesis.

Rising investments in genomic research

Government agencies, private foundations, and venture capitalists are all making significant investments in genomic research. This financing supports a wide range of studies, including some that require bespoke gene synthesis, which increases demand for these services. As genomic research focuses on precision medicine, which tailors treatments to individual genetic profiles, there is an increase in the demand for synthetic genes that can be utilized to produce tailored therapeutics. The demand for tailored treatments is considerably impelling the gene synthesis market growth. Investments in genomic research result in a greater understanding of the genetic basis of diseases, allowing for the creation of new diagnostic tools and therapeutic techniques. These advancements frequently necessitate the creation of synthetic genes for experimental and validation purposes.

Key Market Segmentation: 

IMARC Group provides an analysis of the key trends in each segment of the global gene synthesis market, along with forecasts at the global, regional, and country levels from 2024-2032. Our report has categorized the market based on method, services, application and end use. 

Method Insights:

• Solid-Phase Synthesis
• Chip-Based Synthesis 
• PCR-Based Enzyme Synthesis
   

The report has provided a detailed breakup and analysis of the gene synthesis market based on the method. This includes solid-phase synthesis, chip-based synthesis, and PCR-based enzyme synthesis. According to the report, solid-phase synthesis represented the largest segment. 

Services Insights: 

• Antibody DNA Synthesis
• Viral DNA Synthesis
• Others
   

The report has provided a detailed breakup and analysis of the gene synthesis market based on the services. This includes antibody DNA synthesis, viral DNA synthesis, and others. According to the report, antibody DNA synthesis represented the largest segment. 

Application Insights: 

• Gene and Cell Therapy Development
• Vaccine Development
• Disease Diagnosis
• Others
   

The report has provided a detailed breakup and analysis of the gene synthesis market based on the application. This includes gene and cell therapy development, vaccine development, disease diagnosis and others. According to the report, gene and cell therapy development represented the largest segment. 

End Use Insights: 

• Biotechnology and Pharmaceutical Companies
• Academic and Government Research Institutes
• Contract Research Organizations
   

A detailed breakup and analysis of the gene synthesis market based on the end use has also been provided in the report. This includes biotechnology and pharmaceutical companies, academic and government research institutes, and contract research organizations. According to the report, academic and government research institutes accounted for the largest gene synthesis market share. 

Regional Insights:

• North America 
  • United States 
  • Canada 
• Europe 
  • Germany 
  • France 
  • United Kingdom 
  • Italy 
  • Spain 
  • Others 
• Asia Pacific 
  • China 
  • Japan 
  • India 
  • South Korea 
  • Australia 
  • Indonesia 
  • Others 
• Latin America 
  • Brazil 
  • Mexico 
  • Others 
• Middle East and Africa 
   

The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America was the largest market for gene synthesis. Some of the factors driving the North America gene synthesis market included numerous technological advancements, inflating disposable income levels, considerable growth in the biotechnology industry, etc.

Competitive Landscape: 

The report has also provided a comprehensive analysis of the competitive landscape in the global gene synthesis market. Competitive analysis such as market structure, market share by key players, player positioning, top winning strategies, competitive dashboard, and company evaluation quadrant has been covered in the report. Also, detailed profiles of all major companies have been provided. Some of the companies covered include:

• ATUM
• Boster Biological Technology
• Eurofins Genomics
• Genewiz Inc. (Azenta Life Sciences)
• Genscript Biotech Corp.
• Integrated DNA Technologies Inc.
• Merck KGaA
• OriGene Technologies Inc.
• ProMab Biotechnologies Inc.
• ProteoGenix Inc
• Thermo Fisher Scientific Inc.
• Twist Bioscience
   

Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report. 

Gene Synthesis Market News:

• September 2024: The Center for Health Security announced the Gene Synthesis Screening Information Hub, a new online platform dedicated to help nucleic acid synthesis providers, manufacturers, and customers to adhere to a new federal Framework aimed at preventing intentional misuse of synthetic nucleic acids and supporting safe scientific research practices in the United States.

Report Coverage:

Key Questions Answered in This Report: 

• How has the global gene synthesis market performed so far, and how will it perform in the coming years? 
• What are the drivers, restraints, and opportunities in the global gene synthesis market? 
• What is the impact of each driver, restraint, and opportunity on the global gene synthesis market? 
• What are the key regional markets? 
• Which countries represent the most attractive gene synthesis market? 
• What is the breakup of the market based on the method? 
• Which is the most attractive method in the gene synthesis market? 
• What is the breakup of the market based on the services? 
• Which are the most attractive services in the gene synthesis market? 
• What is the breakup of the market based on the application? 
• Which is the most attractive application in the gene synthesis market? 
• What is the breakup of the market based on the end use? 
• Which is the most attractive end use in the gene synthesis market? 
• What is the competitive structure of the global gene synthesis market? 
• Who are the key players/companies in the global gene synthesis market? 

Key Benefits for Stakeholders:

• IMARC’s report offers a comprehensive quantitative analysis of various market segments, historical and current market trends, market forecasts, and dynamics of the gene synthesis market from 2018-2032.
• The research study provides the latest information on the market drivers, challenges, and opportunities in the global gene synthesis market.
• The study maps the leading, as well as the fastest-growing, regional markets. It further enables stakeholders to identify the key country-level markets within each region. 
• Porter's five forces analysis assist stakeholders in assessing the impact of new entrants, competitive rivalry, supplier power, buyer power, and the threat of substitution. It helps stakeholders to analyze the level of competition within the gene synthesis industry and its attractiveness. 
• Competitive landscape allows stakeholders to understand their competitive environment and provides an insight into the current positions of key players in the market.