The 7 major cryopyrin-associated periodic syndrome markets are expected to exhibit a CAGR of 4.23% during 2024-2034.
Report Attribute
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Key Statistics
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Base Year
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2023
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Forecast Years
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2024-2034
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Historical Years
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2018-2023
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Market Growth Rate 2024-2034 | 4.23% |
The cryopyrin-associated periodic syndrome market has been comprehensively analyzed in IMARC's new report titled "Cryopyrin-Associated Periodic Syndrome Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Cryopyrin-associated periodic syndrome (CAPS) refers to an autoinflammatory disorder characterized by dysregulation of the innate immune system. It encompasses a group of inherited conditions caused by mutations in the NLRP3 gene, resulting in overproduction of interleukin-1β and subsequent inflammation. CAPS manifests with recurring episodes of fever, rash, joint pain, eye redness or conjunctivitis, and neurological issues. These indications often vary in intensity and duration, with some patients experiencing mild, intermittent episodes while others suffer from severe, prolonged manifestations. The diagnosis of CAPS usually requires a combination of clinical symptoms, family history, and laboratory tests. Elevated levels of specific markers like C-reactive protein and serum amyloid A are often observed during flares, supporting the diagnosis. Genetic testing for NLRP3 mutations is a crucial step in confirming the condition. Differential diagnosis is important to distinguish CAPS from numerous other inflammatory diseases, as the treatment approach can vary significantly.
The escalating prevalence of mutations in the NLRP3 gene, which trigger excessive inflammation in tissues and organs, is primarily driving the cryopyrin-associated periodic syndrome market. In addition to this, the inflating utilization of effective treatments, such as interleukin-1 (IL-1) inhibitors, which specifically target the exaggerated IL-1 response and mitigate the inflammatory cascades, is also creating a positive outlook for the market. Moreover, the widespread adoption of supportive therapies like physiotherapy and pain management strategies to aid in enhancing the quality of life by addressing mobility issues and minimizing discomfort in individuals suffering from CAPS is further bolstering the market growth. Apart from this, the rising usage of targeted therapies and precision medicine, since they involve tailoring treatment plans to the patient’s genetic makeup, is acting as another significant growth-inducing factor. Additionally, the increasing research in the areas of immunology and genomics, leading to the development of next-generation therapies that can offer lasting relief from the debilitating symptoms of CAPS with minimal side effects, is also augmenting the market growth. Furthermore, the emerging popularity of telemedicine services for remote monitoring and consultations owing to their numerous benefits, like enhancing patient accessibility to specialized care, is expected to drive the cryopyrin-associated periodic syndrome market during the forecast period.
IMARC Group's new report provides an exhaustive analysis of the cryopyrin-associated periodic syndrome market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for cryopyrin-associated periodic syndrome and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the cryopyrin-associated periodic syndrome market in any manner.
Time Period of the Study
Countries Covered
Analysis Covered Across Each Country
This report also provides a detailed analysis of the current cryopyrin-associated periodic syndrome marketed drugs and late-stage pipeline drugs.
In-Market Drugs
Late-Stage Pipeline Drugs
Drugs |
Company Name
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Ilaris (Canakinumab) | Novartis |
Arcalyst (Rilonacept) | Kiniksa Pharmaceuticals/Regeneron Pharmaceuticals |
Kineret (Anakinra) | Swedish Orphan Biovitrum |
VTX 2735 | Zomagen Biosciences |
Elranatamab | Pfizer |
Iberdomide | Celgene, Bristol-Myers Squibb |
Masitinib | AB Science |
Nivolumab | Bristol-Myers Squibb/Ono Pharmaceuticals |
*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.
Market Insights
Epidemiology Insights
Cryopyrin-Associated Periodic Syndrome: Current Treatment Scenario, Marketed Drugs and Emerging Therapies