The 7 major congenital hyperinsulinism markets reached a value of US$ 112.3 Million in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 180.9 Million by 2034, exhibiting a growth rate (CAGR) of 4.43% during 2024-2034.
Report Attribute
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Key Statistics
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---|---|
Base Year |
2023
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Forecast Years | 2024-2034 |
Historical Years |
2018-2034
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Market Size in 2023
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US$ 112.3 Million |
Market Forecast in 2034
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US$ 180.9 Million |
Market Growth Rate 2024-2034
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4.43% |
The congenital hyperinsulinism market has been comprehensively analyzed in IMARC's new report titled "Congenital Hyperinsulinism Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Congenital hyperinsulinism (CHI) refers to a rare genetic disorder characterized by excessive insulin production in the pancreas, leading to low blood sugar levels (hypoglycemia). This condition primarily affects newborns and infants, posing significant health risks if not promptly diagnosed and managed. The symptoms of CHI can manifest as irritability, seizures, lethargy, and difficulty feeding, as the brain's energy supply is compromised due to low blood sugar. These indications can vary widely, ranging from mild to severe. Individuals suffering from the ailment may also experience developmental delays, brain damage, or life-threatening complications. The diagnosis of CHI involves various clinical and laboratory assessments. The healthcare professional will recommend blood workups to measure glucose and insulin levels in the body. Genetic testing is also performed to identify specific gene mutations responsible for the disorder. Imaging studies, like ultrasound or MRI, may help to visualize the pancreas and rule out numerous other causes of hypoglycemia.
The increasing cases of genetic anomalies affecting key genes like ABCC8 and KCNJ11 that disrupt the normal production of insulin and lead to severe hypoglycemia are primarily driving the congenital hyperinsulinism market. In addition to this, the inflating utilization of effective medical interventions, such as diazoxide, octreotide, glucagon, etc., aimed at managing the condition and averting potential complications, is also creating a positive outlook for the market. Moreover, the widespread adoption of dietary adjustments and continuous glucose monitoring systems for maintaining optimal blood sugar levels and preventing neurological damage is further propelling the market growth. These strategies enable precise glucose management and lessen the long-term impact on cognitive development. Apart from this, the rising usage of pancreatectomy, a surgical intervention that involves partial or complete removal of the pancreas to treat patients who became resistant to medical treatments, is acting as another significant growth-inducing factor. Additionally, the emerging popularity of genetic counseling and testing to help in evaluating risks and inheritance patterns associated with the condition is also augmenting the market growth. Furthermore, the escalating demand for gene therapy, since it involves introducing functional genetic material into cells, thereby rectifying or replacing malfunctioning genes linked to the disorder, is expected to drive the congenital hyperinsulinism market during the forecast period.
IMARC Group's new report provides an exhaustive analysis of the congenital hyperinsulinism market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for congenital hyperinsulinism and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the congenital hyperinsulinism market in any manner.
Time Period of the Study
Countries Covered
Analysis Covered Across Each Country
This report also provides a detailed analysis of the current congenital hyperinsulinism marketed drugs and late-stage pipeline drugs.
In-Market Drugs
Late-Stage Pipeline Drugs
Drugs | Company Name |
---|---|
Proglycem (Oral Diazoxide) | Teva Pharmaceuticals |
HM15136 | Hanmi Pharmaceutical |
Dasiglucagon | Zealand Pharma/Novo Nordisk |
Avexitide | Eiger BioPharmaceuticals |
*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.
Market Insights
Epidemiology Insights
Congenital Hyperinsulinism: Current Treatment Scenario, Marketed Drugs and Emerging Therapies