The 7 major complement 3 glomerulopathy markets reached a value of US$ 9.1 Billion in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 11.8 Billion by 2034, exhibiting a growth rate (CAGR) of 2.46% during 2024-2034.
Report Attribute
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Key Statistics
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Base Year |
2023
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Forecast Years | 2024-2034 |
Historical Years |
2018-2023
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Market Size in 2023
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US$ 9.1 Billion |
Market Forecast in 2034
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US$ 11.8 Billion |
Market Growth Rate 2024-2034 | 2.46% |
The complement 3 glomerulopathy market has been comprehensively analyzed in IMARC's new report titled "Complement 3 Glomerulopathy Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Complement 3 glomerulopathy (C3G) is a rare kidney disorder characterized by the abnormal deposition of complement component C3 in the glomeruli of the kidney. The complement system is an integral part of the immune system that helps protect the body from infection and other threats. Some of the common symptoms of C3G are hematuria, which is the presence of blood in the urine, and proteinuria, which is distinguished by an abundance of protein in the urine. Various other indications include edema, hypertension, renal impairment, etc. The diagnosis of complement 3 glomerulopathy requires a combination of clinical evaluation, laboratory investigations, and imaging studies. Several urine tests, such as urinalysis and urine protein-to-creatinine ratio, are used to identify the presence and severity of proteinuria and hematuria. In addition to this, various blood tests, including serum creatinine, blood urea nitrogen (BUN), estimated glomerular filtration rate (eGFR), etc., are conducted to assess renal function. The gold standard for diagnosis is kidney biopsy, which entails obtaining a tiny sample of kidney tissue and studying it under a microscope to see whether C3 deposits are present in the glomeruli. Besides this, complement activity assays, imaging studies, immunofluorescence staining, and genetic testing can also aid in diagnosing C3G.
The increasing prevalence of autoimmune diseases and the growing need for therapeutics that can efficiently treat the symptoms and slow the progression of the ailment are primarily driving the complement 3 glomerulopathy market. In addition to this, the rising usage of immunosuppressive medications, including corticosteroids, cyclophosphamide, mycophenolate mofetil, etc., to reduce inflammation is also creating a positive outlook for the market. Moreover, the emerging popularity of combination therapies over single-agent therapies on account of their several associated benefits, such as tailored treatment to individual patient needs and reduced risk of side effects, is also augmenting the market growth. Apart from this, the widespread adoption of complement inhibitors, which selectively block the activity of the complement system, a vital part of the immune system involved in the development of C3G, for treating the ailment is further propelling the market growth. Additionally, numerous key players are exploring the use of biomarkers that can aid in identifying specific molecular or genetic characteristics of patients for personalizing the treatment to their particular needs. This, in turn, is acting as another significant growth-inducing factor. Furthermore, ongoing advancements in the field of diagnostics, including the introduction of immunofluorescence staining for identifying the deposition of complement component C3 in the glomeruli of the kidney, are expected to drive the complement 3 glomerulopathy market in the coming years.
IMARC Group's new report provides an exhaustive analysis of the complement 3 glomerulopathy market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for complement 3 glomerulopathy and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the complement 3 glomerulopathy market in any manner.
Time Period of the Study
Countries Covered
Analysis Covered Across Each Country
This report also provides a detailed analysis of the current complement 3 glomerulopathy marketed drugs and late-stage pipeline drugs.
In-Market Drugs
Late-Stage Pipeline Drugs
Drugs | Company Name |
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Iptacopan | Novartis Pharmaceuticals |
KP104 | Kira Pharmaceuticals |
Pegcetacoplan | Apellis Pharmaceuticals/Swedish Orphan Biovitrum |
AMY-101 | Amyndas Pharmaceuticals |
ARO-C3 | Arrowhead Pharmaceuticals |
*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.
Market Insights
Epidemiology Insights
Complement 3 Glomerulopathy: Current Treatment Scenario, Marketed Drugs and Emerging Therapies