Global Male Infertility Market Expected to Reach USD 6.3 Billion by 2033 - IMARC Group

Global Male Infertility Market Statistics, Outlook and Regional Analysis 2025-2033

The global male infertility market size was valued at USD 4.2 Billion in 2024, and it is expected to reach USD 6.3 Billion by 2033, exhibiting a growth rate (CAGR) of 4.51% from 2025 to 2033.

The global male infertility market is being driven by rising awareness about male reproductive health, supported by increased educational campaigns and healthcare access. The accelerating shift towards recognizing male infertility as a major factor in reproductive challenges is leading to a growing demand for fertility testing and treatment. This shift is further fueled by a rise in lifestyle-related factors such as poor diet, lack of exercise, smoking, and stress, which contribute to declining sperm quality. According to a report by National Library of Medicine, it has been estimated that in North America, 4.5% to 6% of the male infertility rates are witnessed, whereas the rate is higher in Australia, at about 9%. In the Eastern European regions, the rate ranges between 8% and 12%. Bayasgalan et al. showed that only 25.6% of infertility cases resulted from male factors. Another study by Thonneau et al. showed that 20% of cases of infertility were due exclusively to male factors in France. As more men become aware of the impact these factors have on fertility, they are seeking timely solutions, creating a substantial growth opportunity for diagnostic services, fertility clinics, and treatment providers across the globe.

Technological advancements and innovation in reproductive medicine also play a critical role in driving the market. On 4^th July 2024, Nikon Corporation announced the launching of the ECLIPSE Ti2-I Motorized Inverted Microscope by July 5, especially for use in micro-insemination. The new model improved efficiency in operation by condensing the steps needed almost by 75%. Further, it has automatic adjustments of microscope settings through soft buttons and a touchscreen. Moreover, an alarm function and a bright, well-defined field of view improve accuracy and precision in manipulating the device. The development of advanced diagnostic techniques, such as semen analysis and genetic testing, has enabled earlier detection and more accurate treatment plans for male infertility. Additionally, improved fertility treatments, including sperm retrieval technologies, hormone therapy, and in vitro fertilization (IVF) procedures tailored to men, have enhanced success rates, further driving demand. With healthcare systems continuously adopting cutting-edge reproductive technologies, the global male infertility market is expanding rapidly. Moreover, increasing collaboration between key industry players is fostering the introduction of more effective and accessible infertility treatments worldwide.

Global Male Infertility Market Statistics, By Region

The market research report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia-Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, Europe accounted for the largest market share on account of advanced healthcare infrastructure, high awareness, and strong support for fertility treatments. Additionally, the region's aging population and changing lifestyles contribute to the growing demand for infertility services.

Europe Male Infertility Market Trends:

Europe is the largest regional segment in the global male infertility market, driven by a combination of advanced healthcare infrastructure, high awareness of reproductive health, and strong research and development capabilities. The region benefits from well-established healthcare systems that provide comprehensive infertility diagnosis and treatment options, which are widely accessible to the population. Furthermore, increasing awareness of male infertility issues, coupled with a growing focus on advanced fertility treatments, is enhancing demand across European countries. According to a research report by IMARC Group, the Europe artificial insemination market size reached US$ 577.5 Million in ​2023​. The market is expected to reach US$ 1,035.22 Million by ​2032​, exhibiting a growth rate (CAGR) of 6.30% during 2024-2032. Government support for healthcare initiatives, along with the presence of leading fertility clinics and medical professionals, also contributes to the market growth. Additionally, Europe's aging population and changing lifestyle habits, such as stress and unhealthy diets, further fuel the need for male infertility services, positioning the region as a key driver in the global market.

Asia Pacific Male Infertility Market Trends:

The Asia Pacific region is growing rapidly in the male infertility market due to growing health awareness and lifestyle disorders such as improper diet, stress, and pollution. China, India, and Japan are states where more fertility treatments are being accepted, accompanied by developments in medical technology and enhanced availability of specialized care. Increasing disposable incomes and changing healthcare policies are also furthering the growth of this market in this region.

North America Male Infertility Market Trends:

North America is a considerable shareholder in the global male infertility market, largely due to high awareness and advanced healthcare systems. The region encompasses well-developed fertility clinics, modern reproductive technologies, and a greater prevalence of infertility treatments. In addition, the growth of demand for personalized care and improved diagnostic methods as well as the increasing acceptance of fertility interventions in society supports the growth of this market in the United States and Canada.

Latin America Male Infertility Market Trends:

Male infertility in Latin America is growing as the number of persons going in for infertility treatments increases. The number has been increasing due to improved awareness of male reproductive health, changes in hospital infrastructure, and fertility services made easily available to consumers. Countries including Brazil and Mexico are witnessing the development of specialized fertility centers, which offer advanced treatments. Additionally, economic development and rising disposable incomes are making infertility solutions more accessible across the region.

Middle East and Africa Male Infertility Market Trends:

The male infertility market in the Middle East and Africa is growing steadily due to increasing awareness and improving access to healthcare. The region still has cultural challenges in some countries, but the health systems of these countries are changing very rapidly, making fertility treatments more acceptable. The demand for assisted reproductive technologies is rising, especially in the GCC countries where wealthier populations are seeking more advanced care for infertility.

Top Companies Leading in the Male Infertility Industry

Some of the leading male infertility market companies include Andrology Solutions, CinnaGen Co., Halotech DNA, SCSA Diagnostics Inc., Vitrolife, Zydus Lifesciences Limited, Intas Pharmaceuticals Ltd., Endo International plc, among others. On 23^rd April 2024, the recently established Endo, Inc. stated that it has successfully completed the previously announced acquisition of nearly all of Endo International plc's ("EIP") assets, as planned by EIP's restructuring plan.

Global Male Infertility Market Segmentation Coverage

• On the basis of the test type, the market has been categorized into sperm agglutination, DNA fragmentation technique, oxidative stress analysis, computer assisted semen analysis, sperm penetration assay, and others, wherein DNA fragmentation technique represent the leading segment. This technique identifies DNA damage that can have a significant effect on fertility, especially when the cause of infertility or recurrent miscarriages is unexplained. With increasing recognition of its importance, DNA fragmentation testing is increasingly sought by couples. Improved technology has also enhanced the accuracy of the test, making it more accessible and widely used.
• Based on the treatment, the market is classified into medication and assisted reproductive technology and varicocele surgery, amongst which assisted reproductive technology and varicocele surgery dominate the market. This can be attributed to its high success rates and advanced techniques. ART has been effective in resolving male infertility problems, such as low sperm count or motility. As the use of ART continues to rise, along with medical technology and accessibility, it has become the leading solution for many couples suffering from infertility.
• On the basis of the distribution channel, the market has been divided into hospitals pharmacies, pharmacies and drug stores, and online pharmacies. Among these, hospitals pharmacies account for the majority of the market share due to their widespread accessibility and trusted healthcare services. Hospitals are the main distribution point as they provide all possible fertility treatments and diagnostic services, and patients will reach the pharmacies for all types of medications and over-the-counter products associated with male fertility. Convenience, access to skilled professionals, and well-entrenched healthcare infrastructures make hospitals and pharmacies the main distribution channels for fertility treatments.
• Based on the end user, the market is segregated into hospitals and clinics, fertility centers, research institutes, and others. Fertility centers are the largest end-user segment in the male infertility market, driven by the growing demand for specialized infertility treatments. These centers provide all-inclusive services ranging from diagnosis to semen analysis and state-of-the-art assisted reproduction technologies including IVF and ICSI. Since the cause of male infertility is properly identified, more and more couples visit fertility centers for the kind of care and treatment they provide. Their concern for reproductive health, medical technology that is advanced, and expertise enable them to stand on par with the end-users as market leaders.