Global Isothermal Nucleic Acid Amplification Technology Market to Reach USD 8.2 Billion by 2033, Spurred by Significant Improvement in the Healthcare Sector

January 07, 2025 | Healthcare

The latest report by IMARC Group, titled “Isothermal Nucleic Acid Amplification Technology Market Report by Product (Instruments, Reagents), Technology (Helicase-Dependent Amplification (HDA), Nicking Enzyme Amplification Reaction (NEAR), Loop-Mediated Isothermal Amplification (LAMP), Strand Displacement Amplification (SDA), Nucleic Acid Sequence-Based Amplification (NASBA), Transcription Mediated Amplification (TMA), Single Primer Isothermal Amplification (SPIA), and Others), Application (Infectious Disease Diagnosis, Blood Screening, and Others), End-User (Hospitals, Diagnostic Laboratories, Research Laboratories, and Others), and Region 2025-2033,” finds that the global isothermal nucleic acid amplification technology market size reached USD 3.4 Billion in 2024. Isothermal nucleic acid amplification technology (INAAT) refers to the technique of detecting and analyzing nucleic acids. This method is commonly used to amplify nucleic acids at a constant temperature, eliminating the need for thermocycler equipment. In addition, the amplicons produced by this technique are utilized to construct versatile nucleic acid nanomaterials for applications in biomedicine, bioimaging, and biosensing. Owing to these properties, INAAT finds extensive applications in the healthcare sector for detecting various infectious diseases, such as HIV-AIDS, tuberculosis, influenza, hepatitis A and B, chlamydia and gonorrhea (CT/NG). 

Global Isothermal Nucleic Acid Amplification Technology Market Trends:

The market is primarily driven by the increasing adoption of INAAT for detecting coronavirus disease (COVID-19). In addition, the rising prevalence of chronic diseases and the escalating demand for efficient diagnosis and treatment alternatives are contributing to the market growth. Besides this, the widespread adoption of loop-mediated isothermal amplification (LAMP) tests that are used for the amplification of both DNA and RNA is also creating a positive market outlook across the globe. Moreover, various technological advancements, such as the development of strand displacement amplification (SDA), single primer isothermal amplification (SPIA) and recombinase polymerase amplification (RPA), along with the introduction of innovative product variants, represent another growth-inducing factor. Furthermore, the increasing research and development (R&D) activities in the field of microbiology, significant improvement in the healthcare infrastructure, and the rising geriatric population are some of the other factors anticipated to propel the market growth in the coming years. Looking forward, IMARC Group expects the market value to reach USD 8.2 Billion by 2033, exhibiting a CAGR of 10.3% during the forecast period (2025-2033).

Market Summary:

  • Based on the product, the market has been bifurcated into instruments and reagents.
  • On the basis of technology, the market has been classified into helicase-dependent amplification (HDA), nicking enzyme amplification reaction (NEAR), loop-mediated isothermal amplification (LAMP), strand displacement amplification (SDA), nucleic acid sequence-based amplification (NASBA), transcription-mediated amplification (TMA), single primer isothermal amplification (SPIA), and others.
  • Based on the application, the market has been segmented into infectious disease diagnosis (hepatitis, CT/NG, HIV, influenza, and others), blood screening, and others.
  • On the basis of the end user, the market has been categorized into hospitals, diagnostic laboratories, research laboratories, and others.
  • Region-wise, the market has been divided into North America (the United States and Canada), Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia and others), Europe (Germany, France, the United Kingdom, Italy, Spain, Russia and others), Latin America (Brazil, Mexico and others), and Middle East and Africa.
  • The competitive landscape of the industry has also been examined, with some of the key players being Abbott Laboratories, bioMérieux SA, Becton, Dickinson and Company (BD), Eiken Chemical Co. Ltd., Hologic Inc., Meridian Bioscience Inc., OptiGene Limited, Thermo Fisher Scientific Inc., Tecan Trading AG and Ustar Biotechnologies Ltd. 


Report Scope:

Report Features Details
Base Year of the Analysis 2024
Historical Period 2019-2024
Forecast Period 2025-2033
Units Billion USD
Segment Coverage Product, Technology, Application, End-User, Region
Region Covered  Asia Pacific, Europe, North America, Latin America, Middle East and Africa
Countries Covered United States, Canada, Germany, France, United Kingdom, Italy, Spain, Russia, China, Japan, India, South Korea, Australia, Indonesia, Brazil, Mexico
Companies Covered Abbott Laboratories, bioMérieux, BD (Becton, Dickinson and Company), Eiken Chemical Co. Ltd., Hologic Inc., Meridian Bioscience Inc., OptiGene Limited, Thermo Fisher Scientific Inc., Tecan Trading AG and Ustar Biotechnologies Ltd.
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Global Isothermal Nucleic Acid Amplification Technology Market to Reach USD 8.2 Billion by 2033, Spurred by Significant Improvement in the Healthcare Sector
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