Global Hereditary Angioedema Therapeutic Market to Grow at 6.82% During 2025-2033, Catalyzed by Rising Incidences of the Disease

January 10, 2025 | Healthcare

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IMARC Group’s latest report, titled “Hereditary Angioedema Therapeutic Market Report by Type (Type I Hereditary Angioedema, Type II Hereditary Angioedema, Type III Hereditary Angioedema), Drug Class (C1-Esterase Inhibitor, Bradykinin B2 Receptor Antagonist, Kallikrein Inhibitor, and Others), Treatment Type (Prophylaxis Treatment, On-demand Treatment), Route of Administration (Intravenous, Subcutaneous, Oral), End User (Hospitals, Clinics, Home Healthcare, and Others), and Region 2025-2033,” finds that the global hereditary angioedema therapeutic market size reached USD 3.1 Billion in 2024. Hereditary angioedema, or HAE, refers to a rare genetic disease caused by dysfunctional or lack of C1-inhibitor protein. It is characterized by recurrent episodes of rapid, severe, subcutaneous, and submucosal swelling of the face, airways, hands, intestinal tract, larynx, trachea, or tongue without the appearance of urticarial lesions. It affects the blood vessels and leads to nausea, extreme pain, vomiting, diarrhea, fatigue, muscle ache, tingling, headache, abdominal pain, hoarseness, and mood swings. It also causes fluid leakage through the walls of blood vessels into body tissues. Currently, researchers and manufacturers are focusing on developing novel HAE therapeutics to cater to unmet medical needs.

Global Hereditary Angioedema Therapeutic Market Trends:

The rising incidences of HAE and the surging awareness about the available HAE therapeutics represent the primary factors driving the market growth. Moreover, the increasing cases of genetic mutations contributing to the disorder is another major growth-inducing factor. In addition, governments of various countries are taking favorable initiatives to promote faster diagnosis and deliver optimal standards of treatment and care to patients. Besides this, the surging demand for preventive medical care to prevent future illness and treatment has accelerated the product adoption rate. Furthermore, several key players are investing heavily in research and development (R&D) activities to enhance HAE therapeutics development. In line with this, the rising public and private funding for rare genetic diseases and orphan drugs have catalyzed market growth. Apart from this, the growing popularity of subcutaneously-administered therapies due to their convenient dosing and higher efficacy than intravenously administered drugs has augmented the product demand. Other factors, including the expanding healthcare industry, increasing regulatory approvals, rising research partnerships, supportive reimbursement policies, and technological advancements, are also providing a positive thrust to the market growth. Looking forward, the market value is projected to reach USD 5.9 Billion by 2033, expanding at a CAGR of 6.82% during 2025-2033.

Market Summary:

The market has been categorized based on the type into type I, type II, and type III hereditary angioedema.
Based on the drug class, the market has been segmented into C-1 esterase inhibitor, bradykinin B2 receptor antagonist, kallikrein inhibitor, and others.
On the basis of the treatment type, the market has been bifurcated into prophylaxis and on-demand treatment.
The market has been divided based on the route of administration into intravenous, subcutaneous, and oral.
Based on the end user, the market has been classified into hospitals, clinics, home healthcare, and others.
Region-wise, the market has been segregated into North America (the United States and Canada), Asia-Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others), Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others), Latin America (Brazil, Mexico, and others), and the Middle East and Africa.
The competitive landscape of the market has also been analyzed, with some of the key players being Adverum Biotechnologies Inc., Amgen Inc., Attune Pharmaceuticals, BioCryst Pharmaceuticals Inc., Centogene N.V., CSL Limited, Ionis Pharmaceuticals Inc., KalVista Pharmaceuticals Inc., Novartis AG, Pharming Group N.V., Sanofi S.A., and Takeda Pharmaceutical Company Limited.

Report Scope:

Report Features	Details
Base Year of the Analysis	2024
Historical Period	2019-2024
Forecast Period	2025-2033
Units	Billion USD
Segment Coverage	Type, Drug Class, Treatment Type, Route of Administration, End User, Region
Region Covered	Asia Pacific, Europe, North America, Latin America, Middle East and Africa
Countries Covered	United States, Canada, Germany, France, United Kingdom, Italy, Spain, Russia, China, Japan, India, South Korea, Australia, Indonesia, Brazil, Mexico
Companies Covered	Adverum Biotechnologies Inc., Amgen Inc., Attune Pharmaceuticals, BioCryst Pharmaceuticals Inc., Centogene N.V., CSL Limited, Ionis Pharmaceuticals Inc., KalVista Pharmaceuticals Inc., Novartis AG, Pharming Group N.V., Sanofi S.A. and Takeda Pharmaceutical Company Limited
Customization Scope	10% Free Customization
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Global Hereditary Angioedema Therapeutic Market to Grow at 6.82% During 2025-2033, Catalyzed by Rising Incidences of the Disease

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