Global Bone Graft and Substitutes Market to Grow at 5% During 2025-2033, Supported by Rising Incidences of Musculoskeletal Disorders

November 19, 2024 | Healthcare

According to the latest report by IMARC Group, titled “Bone Graft and Substitutes Market Report by Material Type (Allografts, Bone Graft Substitutes, Cell-based Matrices, and Others), Application (Spinal Fusion, Trauma, Joint Reconstruction, Foot and Ankle, Dental Bone Grafting, Craniomaxillofacial, and Others), End User (Hospitals, Surgical Centres, Clinics, and Others), and Region 2025-2033,” the global bone graft and substitutes market ireached USD 3.4 Billion in 2024. Bone graft and substitutes are synthetic, inorganic, or biologically organic combinations that are utilized for replacing missing bones or defects. They are commercially available in pellets, moldable putty, injectables, and solid block forms. Bone graft and substitutes are composed of osteoconductive matric, osteoinductive proteins, demineralized bone matrix, platelet-rick plasma, tricalcium phosphate ceramics, and other polymer-based substitutes. These materials are thermally nonconductive, bioresorbable in nature, cause no antigen-antibody reaction, and do not evoke an adverse inflammatory response. This, in turn, promotes wound healing, supports mitogenesis of identical bone cells, and aids in new bone formation.

Global Bone Graft and Substitutes Market Trends:

The global bone graft and substitutes market is primarily being driven by the rising prevalence of musculoskeletal disorders, particularly in the geriatric population. This, in turn, has resulted in the advent of new polymer and ceramic products that have biologically superior characteristics. The development of new manufacturing technologies, such as rapid prototyping and three-dimensional (3D) printing, is further aiding in the fabrication of free-form biomaterial scaffolds for tissue regeneration. Moreover, increasing awareness regarding the benefits of bone regeneration through bone grafts, along with rising inclination toward minimally invasive procedures, is fueling the market growth. Other factors, including the widespread product adoption in facial, spinal, and trauma surgeries and their easy availability in diverse shapes and sizes, are creating a positive outlook for the market further. Looking forward, the market value is projected to reach USD 5.2 Billion by 2033, expanding at a CAGR of 5% during 2025-2033.

Market Summary:

  • Based on the material type, the market has been divided into allografts (machined allografts and demineralized bone matrix (DBMs), bone graft substitutes (bone morphogenic proteins (BMPs) and synthetic bone grafts), cell-based matrices, and others. 
  • On the basis of the application, the market has been classified into spinal fusion, trauma, joint reconstruction, foot and ankle, dental bone grafting, craniomaxillofacial, and others. 
  • Based on the end user, the market has been segmented into hospitals, surgical centres, clinics, and others. 
  • On the geographical front, the market has been segregated into North America, Europe, Asia Pacific, Latin America, and Middle East and Africa.
  • The competitive landscape of the market has also been examined, with some of the key players being Zimmer Biomet Dental, DePuy Synthes, Wright Medical Technology, Medtronic Plc., Stryker Corporation, NuVasive Inc., Arthrex Inc., Integra LifeSciences, Baxter International Inc., Musculoskeletal Transplant Foundation, Bacterin International Holdings, SeaSpine, LifeNet Health, etc.


Report Coverage:

Report Features Details
Base Year of the Analysis 2024
Historical Period 2019-2024
Forecast Period 2025-2033
Units Billion USD
Segment Coverage Material Type, Application, End User, Region
Region Covered  Asia Pacific, Europe, North America, Latin America, Middle East and Africa
Companies Covered Zimmer Biomet Dental, DePuy Synthes, Wright Medical Technology, Medtronic Plc., Stryker Corporation, NuVasive Inc., Arthrex Inc., Integra LifeSciences, Baxter International Inc., Musculoskeletal Transplant Foundation, Bacterin International Holdings, SeaSpine and LifeNet Health
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Global Bone Graft and Substitutes Market to Grow at 5% During 2025-2033, Supported by Rising Incidences of Musculoskeletal Disorders
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