Biliary Atresia Market Size to Grow at a CAGR of 5.64% during 2024-2034, Impelled by Advancements in Early Detection

December 03, 2024 | Healthcare

VIEW FULL TABLE OF CONTENTS

Biliary Atresia Market Outlook 2024-2034:

The biliary atresia market size is expected to exhibit a CAGR of 5.64% during 2024-2034. The market is driven by the escalating application of gene therapy approaches focused on rectifying or replacing defective genes that may be contributing to the pathogenesis of the underlying illness. Additionally, the development of targeted therapies and innovative treatments is further propelling the market growth.

Advances in Early Detection and Diagnostic Technologies: Driving the Biliary Atresia Market

Advances in early detection and diagnostic technologies are significantly driving growth in the biliary atresia market by improving patient outcomes and enabling timely interventions. Moreover, neonatal screening programs have increasingly incorporated innovative diagnostic tools, such as direct bilirubin testing, to detect signs of cholestasis in newborns. This simple yet effective method has been instrumental in identifying biliary atresia earlier, enabling prompt referral for further evaluation. Additionally, the use of high-resolution ultrasonography and contrast-enhanced imaging has improved the visualization of bile duct abnormalities, facilitating more accurate and non-invasive diagnoses. Besides this, molecular and genetic testing technologies have also emerged as game-changers. Studies identifying genetic markers and molecular pathways associated with biliary atresia are paving the way for precision medicine approaches. These advancements not only enhance early detection but also provide insights into potential therapeutic targets, broadening the scope of treatment options. Moreover, as these diagnostic technologies continue to evolve, they are driving demand for earlier intervention strategies, such as the Kasai procedure, which is most effective when performed within the first few months of life. The integration of these cutting-edge tools into clinical practice is transforming the biliary atresia landscape, fostering market growth while improving outcomes for affected infants.

Development of Novel Therapies and Pharmacological Treatments: Contributing to Market Expansion

The development of novel therapies and pharmacological treatments is playing a pivotal role in the expansion of the biliary atresia market, addressing unmet medical needs, and transforming the management of this rare and severe pediatric liver disease. Emerging therapeutic innovations are reshaping the landscape, offering hope for improved outcomes and expanding the market. Moreover, pharmacological advancements have focused on reducing liver inflammation and fibrosis, two major contributors to disease progression in biliary atresia. Anti-fibrotic drugs and bile acid modulators, such as ursodeoxycholic acid, are being optimized to preserve liver function post-surgery. Additionally, immunomodulatory therapies targeting the immune dysregulation implicated in biliary atresia pathogenesis are showing promise in clinical trials. These therapies aim to slow disease progression and extend the time before liver transplantation becomes necessary. Regenerative medicine is another exciting frontier. Research on cell-based therapies, including stem cell transplantation and liver organoids, seeks to repair damaged liver tissue and restore bile flow. These approaches have the potential to revolutionize treatment by reducing dependence on transplantation. Gene therapy is also emerging as a potential game-changer, particularly for cases linked to genetic mutations. Advances in gene-editing technologies, such as CRISPR-Cas9, are paving the way for correcting the underlying genetic defects driving the disease. The introduction of these novel treatments, combined with continued surgical advancements and supportive care, is bolstering the growth of the market.

Emerging Therapies in Biliary Atresia Market

Maralixibat: Mirum Pharmaceuticals

Maralixibat is an oral, minimally absorbed ileal bile acid transporter (IBAT) inhibitor. It works by inhibiting the apical sodium-dependent bile acid transporter (ASBT) in the small intestine. This prevents bile acids from being reabsorbed into the blood and liver, increasing the amount eliminated in the stool. This lowers bile acid levels in the body, potentially decreasing bile acid-related liver damage and consequences.

Drug Name	Company Name	MOA	ROA
Maralixibat	Mirum Pharmaceuticals	Sodium-bile acid cotransporter inhibitors	Oral

Detailed list of emerging therapies in Biliary Atresia is provided in the final report.

Key Players in Biliary Atresia Market:

The key players in the Biliary Atresia market who are in different phases of developing different therapies are Mirum Pharmaceuticals and Others.

Key Players

Regional Analysis:

The major markets for biliary atresia include the United States, Germany, France, the United Kingdom, Italy, Spain, and Japan. According to projections by IMARC, the United States has the largest patient pool for biliary atresia while also representing the biggest market for its treatment. This can be attributed to the growing use of direct bilirubin testing in newborns as part of routine screening, which has significantly improved early detection rates, enabling timely surgical interventions such as the Kasai procedure.

Moreover, pharmaceutical companies and academic institutions are actively exploring novel therapies, including anti-fibrotic drugs, bile acid modulators, and immunomodulatory agents, which aim to slow disease progression and improve long-term outcomes. Furthermore, regenerative medicine and gene therapy research, supported by substantial funding and favorable regulatory frameworks, are paving the way for groundbreaking treatments.

Besides this, patient advocacy and awareness campaigns have also contributed to the market’s growth by educating healthcare professionals and families about the importance of early diagnosis and available treatment options.

Recent Developments in Biliary Atresia Market:

In December 2023, Mirum Pharmaceuticals, Inc. published top-line results from the Phase 2 EMBARK study, which compared LIVMARLI (maralixibat) oral solution to placebo as an adjuvant therapy following Kasai surgery in patients with biliary atresia.

Key information covered in the report.

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the biliary atresia market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the biliary atresia market
Reimbursement scenario in the market
In-market and pipeline drugs

Competitive Landscape:

This report offers a comprehensive analysis of current biliary atresia marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

About Us:

IMARC Group is a global management consulting firm that helps the world’s most ambitious changemakers to create a lasting impact. Across the six major continents and 100+ countries, we work alongside our business partners as one team with a common ambition to achieve unparallelled results, gain a competitive edge, and transform industries. IMARC Group excels in understanding its clients’ business priorities and delivering tailored solutions that drive meaningful outcomes. Our client base spans over 3,000 organizations in the private, public, and social sectors, ranging from high-growth startups to Fortune 500 companies.

Contact US

IMARC Group
134 N 4th St. Brooklyn, NY 11249, USA
Email: Sales@imarcgroup.com
Tel No:(D) +91 120 433 0800
Phone Number: - +1 631 791 1145, +91-120-433-0800

Need more help?

Speak to our experienced analysts for insights on the current market scenarios.
Include additional segments and countries to customize the report as per your requirement.
Gain an unparalleled competitive advantage in your domain by understanding how to utilize the report and positively impacting your operations and revenue.
For further assistance, please connect with our analysts.

Biliary Atresia Market Size to Grow at a CAGR of 5.64% during 2024-2034, Impelled by Advancements in Early Detection

Purchase Options New Year Sale

Inquire Before Buying

Benefits of Customization

Personalize this research
Triangulate with your data
Get data as per your format and definition
Gain a deeper dive into a specific application, geography, customer, or competitor
Any level of personalization

Speak to an Analyst

Request Brochure

Get in Touch With Us

UNITED STATES

Phone: +1-631-791-1145

INDIA

Phone: +91-120-433-0800

UNITED KINGDOM

Phone: +44-753-714-6104

Email: sales@imarcgroup.com

Client Testimonials

IMARC made the whole process easy. Everyone I spoke with via email was polite, easy to deal with, kept their promises regarding delivery timelines and were solutions focused. From my first contact, I was grateful for the professionalism shown by the whole IMARC team. I recommend IMARC to all that need timely, affordable information and advice. My experience with IMARC was excellent and I can not fault it.

The IMARC team was very reactive and flexible with regard to our requests. A very good overall experience. We are happy with the work that IMARC has provided, very complete and detailed. It has contributed to our business needs and provided the market visibility that we required

We were very happy with the collaboration between IMARC and Colruyt. Not only were your prices competitive, IMARC was also pretty fast in understanding the scope and our needs for this project. Even though it was not an easy task, performing a market research during the COVID-19 pandemic, you were able to get us the necessary information we needed. The IMARC team was very easy to work with and they showed us that it would go the extra mile if we needed anything extra

Last project executed by your team was as per our expectations. We also would like to associate for more assignments this year. Kudos to your team.

We would be happy to reach out to IMARC again, if we need Market Research/Consulting/Consumer Research or any associated service. Overall experience was good, and the data points were quite helpful.

Arabian Plastic Manufacturing Company Ltd.

The figures of market study were very close to our assumed figures. The presentation of the study was neat and easy to analyse. The requested details of the study were fulfilled. My overall experience with the IMARC Team was satisfactory.

The overall cost of the services were within our expectations. I was happy to have good communications in a timely manner. It was a great and quick way to have the information I needed.

My questions and concerns were answered in a satisfied way. The costs of the services were within our expectations. My overall experience with the IMARC Team was very good.

I agree the report was timely delivered, meeting the key objectives of the engagement. We had some discussion on the contents, adjustments were made fast and accurate. The response time was minimum in each case. Very good. You have a satisfied customer.

We would be happy to reach out to IMARC for more market reports in the future. The response from the account sales manager was very good. I appreciate the timely follow ups and post purchase support from the team. My overall experience with IMARC was good.

IMARC was a good solution for the data points that we really needed and couldn't find elsewhere. The team was easy to work, quick to respond, and flexible to our customization requests.

IMARC did an outstanding job in preparing our study. They were punctual and precise, delivering all the data we required in a clear and well-organized format. Their attention to detail and ability to meet deadlines was impressive, making them a reliable partner for our project.

I wanted to express my sincere appreciation for your efforts in handling this matter. Your dedication and commitment have truly been commendable. It is evident that you have put in a tremendous amount of hard work and expertise into resolving the issues at hand. I would also like to take this opportunity to inform you that we are greatly interested

Overall, the deliverable was well organized and my experience with the project team was good. In particular, I appreciated how they responded when I requested additional information and the Japanese version.

The IMARC team were extremely professional and very cooperative. The team were also extremely flexible in making changes and modifications wherever required. The entire experience right from project kick-off to after sales support was fruitful and smooth.

I’d like to express my gratitude for the work you accomplished with the industry report. The way you responded to the requirements and delivered under tight timelines shows your expertise, exceptional work ethic and commitment to your customer’s success. The entire team and company are incredibly thankful for your dedication. Once again, thank you

The market reports from IMARC have been instrumental in guiding our business strategies. We found the reports comprehensive and data-driven, which helped us make informed decisions. The detailed insights and actionable data have consistently provided us with a competitive edge in a rapidly changing alcohol market.

One of the best things about IMARC is their flexibility and predisposition to tailor the reports and adapt to our needs. They are not just great in their researching and consulting solutions, but their service is unparallelled. We’ve worked with them a couple of times and we will keep working with them in future projects.

We recently commissioned multiple market research reports from IMARC, and the insights we received were invaluable. The depth of analysis, accuracy of data, and actionable recommendations have greatly enhanced our strategic decision-making.

The market estimates provided by your team were pretty much in line with what we were theorizing internally. Really appreciate the work on this.

The sale account manager and the service was excellent. The data and market trends gathered from the report was insightful and really assisted while planning future product and growth strategies.

The report is excellent and has good amount of data and our team is extremely happy with the information provided.

Thank you very much for your cooperation and post purchase support. We were really happy with the final deliverable, and the takeaways from the report.